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Intestines and Digestion

The gut is one of the most important organs in our body and plays a key role in our health. In addition to digestion and the absorption of nutrients, it plays a crucial role in the immune system, the body’s detoxification, and the production of certain vitamins and hormones. A healthy microbiome—consisting of approximately 38 trillion bacteria—and an intact intestinal mucosa are crucial for optimal gut function. However, factors such as stress, processed foods, or the use of antibiotics can disrupt the delicate balance of the gut flora. The consequences: digestive problems and a weakened immune system.

This is where a targeted gut restoration program comes in. The combination of probiotic bacteria, prebiotic fiber, and special mucosal nutrients—as found in ourProbiotics Gut Restoration Program Original—can restore the balance of the gut flora. The products included—Pro EM san,Pro Präbioma, andPro Mucosa—not only help regenerate healthy gut flora but also strengthen the intestinal mucosa and promote optimal digestion.

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf
5.0 out of 5 stars


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also worth highlighting is that the products are based on the latest scientific findings and take into account the company’s own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg
5.0 out of 5 stars


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO’s highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance
5.0 out of 5 stars


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports my patients’ health.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter
5.0 out of 5 stars


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from naturopaths for naturopaths, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it to others!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, Alternative Medicine Practitioner
Potsdam
5.0 out of 5 stars


"I've been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results."

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, alternative medicine practitioner
Trier
5.0 out of 5 stars


“As a naturopath, I apply the TISSO approach specifically to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send
5.0 out of 5 stars


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic treatment approaches and fully meet my standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby
5.0 out of 5 stars


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel
5.0 out of 5 stars


"I really enjoy working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

Which Digestive Enzymes Are Important for Good Digestion

 

Only with good digestion can the nutrients from food be broken down and then absorbed by the body.Digestive enzymes—such as thosefoundin ourPro Enzym—help with this process:

  • Carbohydratesare broken down in the mouth by alpha-amylase, which is found in saliva. In the small intestine, the breakdown of carbohydrates continues with the help of amylase from the pancreas. 
  • Lipases break downfats andare produced primarily in the pancreas and small intestine. They are also found in small amounts in saliva and gastric juice. Fats are absorbed with the help of bile acids, which are produced in the liver. 
  • Proteinsare first modified by stomach acid and then broken down by proteases. Proteases are produced in the stomach, the duodenum, and the pancreas. 

Tip:The bitter compoundsfound in high concentrations in ourPro IntestandPro Intest Alcohol-Freeproducts can also stimulate digestion and the entire metabolic process. 

A Healthy Intestinal Barrier—The Foundation of Gut Health and the Focus of Gut Restoration

The intestinal barrier consists of:

  • thegut flora,
  • theintestinal mucosa, includingthe mucus layer
  • and a large part ofthe immune system.

80% of immune cells are located in the gut. These include, in particular, neutrophils, macrophages, dendritic cells, and T and B lymphocytes.

Diagram of the intestinal barrier: at the top, the gut microbiota; below that, the immunoglobulin-rich mucus layer (sIgA); the intestinal mucosa with tight junctions; and below that, the gut-associated immune system with macrophages, neutrophils, dendritic cells, plasma cells, B lymphocytes, and T lymphocytes
Function of the Gut Microbiome

The most important component of the intestinal barrier is the gut microbiota. It contains approximately 38 trillion bacteria, which accounts for about 98% of all the bacteria in the body and consists of at least 160 different bacterial species.

The gut microbiota has several beneficial effects on our intestines and the entire body. For example , it is important for:

  • the defense against disease-causing pathogens
  • a healthy digestive system
  • regular bowel movements
  • strengthening the immune system
  • the elimination of harmful toxins
  • the production of lactic acid and short-chain fatty acids for a healthy, acidic intestinal environment; the short-chain fatty acids, especially butyrate, are also used as a source of energy for the intestinal mucosa
Function of the Intestinal Mucosa

The intestinal mucosa consists of a layer of mucosal cells that are closely connected to one another by what are known as tight junctions and allow substances to pass through only in a highly controlled manner. It is important that this layer of cells remains intact and that no gaps form. Otherwise, substances from harmful pathogens or food components can pass through and unintentionally keep the immune system on high alert.

A healthy intestinal flora and a thick mucus layer containing secretory immunoglobulin A (sIgA) are important for a healthy mucous membrane. This immunoglobulin A (IgA) is produced by plasma cells—which develop from B lymphocytes—and is secreted through the epithelial layer. Its function is to ward off harmful pathogens.

A smiling woman in a green sweater, with her hands in front of her stomach
The Goal of Gut Restoration: Rebuilding Healthy Gut Flora

If we have too few good bacteria in our gut, or if the bacterial diversity or the ratio between bacterial strains is out of balance, then the gut flora has become imbalanced—a condition also known as dysbiosis. An imbalance in the gut flora isn’t always immediately noticeable, but it usually manifests as digestive problems, a weakened immune system, or low mood.

What factors can trigger gut dysbiosis?

The following are particularly worth mentioning:

  • an unbalanced, low-fiber diet
  • sugary foods
  • Food Additives
  • Digestive Enzyme Deficiency
  • chronic stress
  • Environmental toxins (pesticides, heavy metals)
  • Cesarean section births
  • Taking medications such as antibiotics
Restoring Balance to the Gut Microbiome

The following are particularly helpful:

  • probiotic bacteria (probiotics)
  • soluble dietary fiber (prebiotics) as food for the good gut bacteria
    balanced diet

Important for a Damaged Intestinal Wall: Regeneration of the Intestinal Mucosa

If you suffer from bloating, abdominal pain, chronic fatigue, or frequent infections, the cause may be an imbalance in the microbiome as well as impaired function of the intestinal wall. The consumption of industrially processed foods, the use of pesticides in conventional agriculture, and exposure to environmental toxins can directly damage the intestinal wall—just as they can damage the gut microbiota.  

The connections between intestinal cells—known as tight junctions—deteriorate and, if the stress persists, can no longer hold the intestinal wall together. This condition is known as leaky gut. If the intestinal wall has gaps, undigested food particles, pathogens, and toxins can enter the bloodstream unchecked. The immune system responds immediately to these foreign substances—which normally have no place in the blood—and releases inflammatory substances. The body goes into constant overdrive and may develop antibodies against food substances that normally do not harm us. This can lead to food intolerances and many other health issues.

With specific phytonutrients and micronutrients, you canspecificallysupportthe regenerationoftheintestinal wall. Important nutrients for the intestinal mucosa—which have been effectively combined inPro Mucosa—include, above all: L-glutamine, lecithin, B vitamins, broccoli extract, and polyphenols such as quercetin and resveratrol. 

What does a colon cleanse—often referred to as a colon detox—involve?

The goal of intestinal restoration is to restore the health of the intestines. This involves rebalancing the gut microbiota, rebuilding the intestinal mucosa, and optimizing digestion. As a result, intestinal and digestive symptoms are often reduced, and overall well-being is improved.

Guide to Gut Detoxification — Here’s what we recommend to get your gut back in shape:

Substance Here's what you should keep in mind Matching Product

Probiotics

high diversity of live lactic acid cultures

Pro EM san

Prebiotics

slow-fermenting dietary fiber that produces less gas in the intestines

Pro EM san

Nutrients for the Mucous Membrane

A combination of B vitamins (B2, B3, B6, biotin), lecithin, the amino acid glutamine, and phytonutrients/polyphenols

Pro Mucosa

Bitter compounds

A blend of various herbs with a high content of bitter compounds, balanced in proportion to one another

Pro Intest

* This refers to a potentially increased need for nutrients and not to the relief, cure, or prevention of a disease.

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EVIDENCE-BASED KNOWLEDGE FOR YOUR HEALTH

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