Really good!
TISSO. From practice for people.
In the late 1990s, naturopath Albert Hesse was looking for a probiotic containing many bacterial strains—he couldn’t find one, so he developed Pro EM san himself, a fermented herbal and plant extract containing 31 lactic acid cultures, which remains one of TISSO’s most successful products to this day. Since 1999, TISSO has been synonymous with high-quality dietary supplements that combine natural ingredients with scientific expertise.
TISSO - WHO WE ARE AND WHAT WE DO
It all began with a naturopath and a few billion gut bacteria: In the late 1990s, Albert Hesse, a naturopath from the Sauerland region, was searching for a good probiotic for his patients that contained as wide a variety of bacterial strains as possible.
Unable to find what he was looking for, he decided to develop a multi-species preparation himself: Pro EM san, a naturally fermented herbal and plant extract containing 31 carefully combined lactic acid bacteria cultures. With this formula—which remains essential to this day—Albert Hesse founded the company TISSO in 1999.
Today, TISSO specializes in the development and manufacture of high-quality natural dietary supplements. The product line currently includes about 60 formulations, which are produced locally in Wenden and distributed internationally.
Quality from Germany = safe products for you!
As a modern, medium-sized company, we are committed to our location in Wenden because we have everything under one roof here—from our in-house R&D department to production, logistics, and sales—including our own bacterial strain collection.
This also offers a clear advantage for you as a customer: You can rest assured that our dietary supplements meet the high quality standards set by German food law and contain only approved ingredients in approved dosages.
Nature doesn't provide single-ingredient supplements. Neither do we. Whether it’s microorganisms for the gut, plant extracts, minerals, amino acids, fatty acids, or vitamins—our formulations combine nutrients just as nature does: in a way that allows them to optimally support and enhance one another. Not only the individual ingredients, but also the formulations themselves are optimally balanced within our nutritional concept.
Health begins at the cellular level: The trillions of cells in our bodies can only perform their many functions if they receive all the nutrients they need. That is the purpose of our formulations. Our nutrient combinations are specifically designed to provide optimal support for the gut and the mitochondria—the “powerhouses of the cells.”
Nature is our source of raw materials. After all, nature simply provides the best ingredients. We use only certified, low-allergen raw materials, which are regularly tested in external laboratories for microbiological contamination as well as for heavy metals, insecticides, pesticides, fungicides, and radioactivity. This ensures the highest possible purity and naturalness for all our products—and, consequently, safety for our customers.
TISSO products contain neither genetically modified raw materials nor any other harmful substances. In addition, we do not use artificial additives such as preservatives, sweeteners, flavorings, or flavor enhancers, nor do we use gluten. Our PET product packaging is regularly tested and manufactured by our contract partners. It contains no phthalates or other plasticizers.
Using our state-of-the-art production technology, we process the raw materials as gently as possible to preserve their natural properties. We also ensure that the ingredients have high bioavailability—so your body can get the most out of our products.
All the products we offer you are based on the latest scientific findings as well as concrete real-world experience. To demonstrate the safety and beneficial properties of our formulations, we conduct studies and observational trials and work closely with laboratories and research institutes. This benefits our products—and, of course, you above all.
TISSO stands for innovative, high-quality dietary supplements that are scientifically sound and practical. It is important to us to incorporate insights from research and therapeutic practice into our product concepts. An interdisciplinary scientific advisory board supports us in this effort: With in-depth expertise, practical experience, and scientific curiosity, the board guides the development of our formulations—for products that deliver results in everyday life.
TISSO QUALITY, BACKED BY A WRITTEN GUARANTEE AND A SEAL

All TISSO products are manufactured in accordance with current GMP (Good Manufacturing Practice) guidelines for food products. This allows us to guarantee consistently high standards of quality and hygiene.

This seal identifies TISSO products that have been successfully tested in scientific studies.
When you contact us, you can be sure that a real person—not a machine—will respond. Our customer service team is available Monday through Friday during regular business hours to provide expert advice and answer any questions you may have about our products.
All from our own culture collection: To ensure that we can always guarantee the highest quality and safety for our microorganism preparations, we maintain our own bacterial culture collection in Wenden. Highly specialized professionals are responsible for the cultivation and maintenance of these cultures. All bacterial strains are regularly genotyped so that we can ensure their consistent properties.
You can rest assured: Our recipes contain no genetically modified ingredients, pesticides, or other harmful substances. In addition, we do not use artificial additives such as preservatives, sweeteners, flavorings, or flavor enhancers, nor do we use gluten.
To ensure quality and to monitor and verify our supply chains and chains of responsibility, regular inspections are conducted in accredited laboratories.
We offer a large portion of our products in capsule form because capsules are generally the optimal dosage form for our nutrient combinations—and because their production requires very few technical excipients and additives.
Just so you know what you're taking: We use high-quality, well-tolerated capsules made from plant-based cellulose (HPMC) or pullulan, and we deliberately avoid carrageenan, polyethylene glycol (PEG), and other unnecessary or questionable ingredients.
WHAT YOU CAN COUNT ON FROM US
That's what makes us special
Nature provides us with so many wonderful things—especially the diverse and amazing ingredients for our nutrient-rich formulations. We want to give something back to nature, conserve resources, and reduce our ecological footprint. For us, high quality and environmental responsibility go hand in hand. That’s why we use green electricity, rely on water from our own rainwater cistern, and have our catalog and promotional materials printed on eco-friendly recycled paper.
We also use raw materials that are as sustainable as possible for our product packaging: Our “Pro EM san” bottles are already made from 100% recycled PET, and we are currently in the process of switching our PET cans entirely to recycled material as well.

Trees are nature’s climate protectors: They produce oxygen, filter CO2 from the air, and use their roots to protect the soil from erosion. Together with Treedom, a global environmental organization, we’re planting new trees in Kenya, Nepal, and Colombia: With 300 fruit and timber trees in our own TISSO Forest, we offer small farmers in a region particularly affected by climate change and deforestation a guaranteed source of agricultural income—while simultaneously offsetting 68,000 kg of carbon dioxide. In the coming years, the TISSO Forest will continue to grow with our support.
A healthy life and well-being for all people.
We promote sustainable health through root-cause treatment based on natural ingredients. We use innovative approaches to raise awareness in society about taking personal responsibility for one’s lifestyle by sharing our expertise.
Hello, animal lover!
Why not treat your pet to something special, too—with the natural dietary supplements from our sister company, PROVICELL!
Many of our customers have always used our recipes for their pets, with excellent results. Based on the TISSO nutritional concept and in close collaboration with veterinarians and animal health practitioners, we have developed our own product line that is specifically tailored to the needs of animals.
For information and to order, visit PROVICELL
