TISSO. From practice for people.

In the late 1990s, naturopath Albert Hesse was looking for a probiotic containing many bacterial strains—he couldn’t find one, so he developed Pro EM san himself, a fermented herbal and plant extract containing 31 lactic acid cultures, which remains one of TISSO’s most successful products to this day. Since 1999, TISSO has been synonymous with high-quality dietary supplements that combine natural ingredients with scientific expertise.

A person’s midsection, with a flowering cherry branch in front of it, casting a shadow on the skin

TISSO - WHO WE ARE AND WHAT WE DO

It all began with a naturopath and a few billion gut bacteria: In the late 1990s, Albert Hesse, a naturopath from the Sauerland region, was searching for a good probiotic for his patients that contained as wide a variety of bacterial strains as possible.

Unable to find what he was looking for, he decided to develop a multi-species preparation himself: Pro EM san, a naturally fermented herbal and plant extract containing 31 carefully combined lactic acid bacteria cultures. With this formula—which remains essential to this day—Albert Hesse founded the company TISSO in 1999.

Today, TISSO specializes in the development and manufacture of high-quality natural dietary supplements. The product line currently includes about 60 formulations, which are produced locally in Wenden and distributed internationally.

Quality from Germany = safe products for you!

As a modern, medium-sized company, we are committed to our location in Wenden because we have everything under one roof here—from our in-house R&D department to production, logistics, and sales—including our own bacterial strain collection.

This also offers a clear advantage for you as a customer: You can rest assured that our dietary supplements meet the high quality standards set by German food law and contain only approved ingredients in approved dosages.

A woman with curly hair is enjoying the sunlight with her eyes closed
NATURE AND RESEARCH EFFECTIVELY COMBINED

THE PEOPLE BEHIND TISSO

Portrait photo of Veit Seemann, CEO

Veit Seemann

CEO
Portrait photo of Mareen Junge, Head of Sales & Marketing

Mareen Junge

Head of Sales and Marketing
Portrait photo of Dr. rer. nat. Reinhard Wähler, a biochemist and Head of Research and Development at TISSO Naturprodukte

Reinhard Wähler

Head of Research and Development
Portrait photo of Sabine Kraus, Event Manager

Sabine Kraus

Event Manager
Portrait photo of Simone Axt, International Sales Manager

Simone Axt

International Sales Manager
Portrait photo of Tina Soemer, National Sales Manager

Tina Soemer

National Sales Manager
Two hands are reaching for a tree trunk, as if they were climbing up it
IT'S ALL ABOUT THE COMBINATION

Nature doesn't provide single-ingredient supplements. Neither do we. Whether it’s microorganisms for the gut, plant extracts, minerals, amino acids, fatty acids, or vitamins—our formulations combine nutrients just as nature does: in a way that allows them to optimally support and enhance one another. Not only the individual ingredients, but also the formulations themselves are optimally balanced within our nutritional concept.

OUR HOLISTIC NUTRITIONAL APPROACH

Health begins at the cellular level: The trillions of cells in our bodies can only perform their many functions if they receive all the nutrients they need. That is the purpose of our formulations. Our nutrient combinations are specifically designed to provide optimal support for the gut and the mitochondria—the “powerhouses of the cells.”

A bottle of TISSO Pro Intest alcohol-free, sitting on moss-covered forest floor among tree fungi
THE HIGHEST QUALITY FROM NATURE

Nature is our source of raw materials. After all, nature simply provides the best ingredients. We use only certified, low-allergen raw materials, which are regularly tested in external laboratories for microbiological contamination as well as for heavy metals, insecticides, pesticides, fungicides, and radioactivity. This ensures the highest possible purity and naturalness for all our products—and, consequently, safety for our customers.

TISSO products contain neither genetically modified raw materials nor any other harmful substances. In addition, we do not use artificial additives such as preservatives, sweeteners, flavorings, or flavor enhancers, nor do we use gluten. Our PET product packaging is regularly tested and manufactured by our contract partners. It contains no phthalates or other plasticizers.

Using our state-of-the-art production technology, we process the raw materials as gently as possible to preserve their natural properties. We also ensure that the ingredients have high bioavailability—so your body can get the most out of our products.

THE BEST OF THEORY AND PRACTICE

All the products we offer you are based on the latest scientific findings as well as concrete real-world experience. To demonstrate the safety and beneficial properties of our formulations, we conduct studies and observational trials and work closely with laboratories and research institutes. This benefits our products—and, of course, you above all.

A person wearing safety goggles and a face mask is looking into a microscope
Two hands meet, palms facing each other, against a backdrop of a vast landscape
SCIENTIFIC ADVISORY BOARD

TISSO stands for innovative, high-quality dietary supplements that are scientifically sound and practical. It is important to us to incorporate insights from research and therapeutic practice into our product concepts. An interdisciplinary scientific advisory board supports us in this effort: With in-depth expertise, practical experience, and scientific curiosity, the board guides the development of our formulations—for products that deliver results in everyday life.

MEMBERS OF THE SCIENTIFIC ADVISORY BOARD

Portrait photo of Prof. Dr. Jan Frank

Prof. Dr. Jan Frank


Prof. Dr. Jan Frank is Dean of the Faculty of Natural Sciences at the University of Hohenheim, where he heads the Chair of Food Biofunctionality. His research focuses, among other things, on the bioavailability of phytochemicals and vitamin E. As president of the Society of Nutrition and Food Science and editor-in-chief of the NFS Journal, he brings in-depth scientific expertise to the advisory board.

Portrait photo of Monique Thill, a naturopath specializing in gut microbiota regulation

Monique Thill


Monique Thill is a naturopath with her own naturopathic practice in Trier. Since 2004, she has been helping people using an integrative, holistic approach, with a special focus on gut health, the immune system, and prevention. In addition to her work at the practice, she is a speaker and author, sharing her knowledge with a wide audience.

Portrait photo of Dr. med. Stefan Springer, physician and specialist in orthopedics

Stefan Springer, M.D.


Dr. Stefan Springer, M.D., is a board-certified specialist in general medicine and orthopedics and has also earned qualifications in several naturopathic disciplines. At his practice in Regensburg, he combines conventional medicine with complementary diagnostic and therapeutic methods. As an experienced practitioner, he regularly gives lectures on alternative healing methods.

TISSO QUALITY, BACKED BY A WRITTEN GUARANTEE AND A SEAL

"GMP Certificate – Good Manufacturing Practice" seal

All TISSO products are manufactured in accordance with current GMP (Good Manufacturing Practice) guidelines for food products. This allows us to guarantee consistently high standards of quality and hygiene.

“TISSO STUDY” seal for products that have been tested in scientific studies

This seal identifies TISSO products that have been successfully tested in scientific studies.

TOP-NOTCH CUSTOMER SERVICE: THAT'S WHAT SETS US APART

When you contact us, you can be sure that a real person—not a machine—will respond. Our customer service team is available Monday through Friday during regular business hours to provide expert advice and answer any questions you may have about our products.

Two hands holding each other—a symbolic image representing personalized customer service

WHAT OUR CUSTOMERS SAY

Excellent
Based on 4348 reviews

Verified Buyer

Really good!

Really good!

Laura Drexler

Oct 20, 2026

Verified Reviewer

Working with nature...free from laboratories and manipulations...may the goal remain quality.

The ingredients, herbal composition, selection, very harmonious, genuine, you can still taste the herb itself. Helps immediately, noticeably. Serious and clear processing when ordering, processed with a consciousness for nature right into the hands of the customer. Pro Intest..

Isabella Wedenig

Oct 20, 2026

Verified Reviewer

Order Processing

Order processing, shipping, and product Pro Mucosa all 100 % 👍👍☺️

Margrit

Oct 20, 2026

Verified Reviewer

Everything is great

Everything is great, quality, price, performance

Siegfried

Oct 20, 2026

Verified Buyer

Maximum precision thanks to Italy

Maximum precision thanks to Italy

Michela Ciuffreda

Oct 19, 2026

Verified Buyer

Super Product

Super product! Fast delivery

Aneta Wozny

Oct 19, 2026

Verified Buyer

Very good quality

Very good quality. Products meet all expectations. Unfortunately, the shipping costs for smaller orders are very high.

Michael Hofmann

Oct 19, 2026

Verified Buyer

I am very satisfied with the…

I am very satisfied with the products. They have already helped me a lot.

Astrid

Oct 18, 2026

MICROORGANISMS FROM OUR OWN CULTURE COLLECTION

All from our own culture collection: To ensure that we can always guarantee the highest quality and safety for our microorganism preparations, we maintain our own bacterial culture collection in Wenden. Highly specialized professionals are responsible for the cultivation and maintenance of these cultures. All bacterial strains are regularly genotyped so that we can ensure their consistent properties.

WHAT WE DON'T PUT IN OUR PRODUCTS

You can rest assured: Our recipes contain no genetically modified ingredients, pesticides, or other harmful substances. In addition, we do not use artificial additives such as preservatives, sweeteners, flavorings, or flavor enhancers, nor do we use gluten.


To ensure quality and to monitor and verify our supply chains and chains of responsibility, regular inspections are conducted in accredited laboratories.

LET'S GET RID OF IT: HIGH-QUALITY, ALL-PLANT-BASED CAPSULES

We offer a large portion of our products in capsule form because capsules are generally the optimal dosage form for our nutrient combinations—and because their production requires very few technical excipients and additives.
Just so you know what you're taking: We use high-quality, well-tolerated capsules made from plant-based cellulose (HPMC) or pullulan, and we deliberately avoid carrageenan, polyethylene glycol (PEG), and other unnecessary or questionable ingredients.

WHAT YOU CAN COUNT ON FROM US

That's what makes us special
A hand holds a capsule next to a glass of water with lemon and ginger
In-house development based on scientific research
Our experts review countless studies for each formula. 
Highly bioavailable and optimally combined
We always select our raw materials to ensure they are as effective as possible. 
Brand-quality products made in-house
We manufacture our products ourselves to ensure the highest quality at all times. 
Nutrient Concept Proves Successful in Practice
More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® concept. 
Expertise Since 1999
Take advantage of our extensive experience with high-quality dietary supplements. 
Guarantee of the Highest Purity
We continuously inspect our products in accordance with the highest quality standards.
An open palm with yellow and white capsules
ENVIRONMENTAL PROTECTION AND SUSTAINABILITY AT TISSO

Nature provides us with so many wonderful things—especially the diverse and amazing ingredients for our nutrient-rich formulations. We want to give something back to nature, conserve resources, and reduce our ecological footprint. For us, high quality and environmental responsibility go hand in hand. That’s why we use green electricity, rely on water from our own rainwater cistern, and have our catalog and promotional materials printed on eco-friendly recycled paper.

We also use raw materials that are as sustainable as possible for our product packaging: Our “Pro EM san” bottles are already made from 100% recycled PET, and we are currently in the process of switching our PET cans entirely to recycled material as well.

Logo: “Proud member of BNW – Bundesverband Nachhaltige Wirtschaft e.V.”
TISSO has been a member of the Federal Association for Sustainable Economy since 2021.
TISSO AND TREEDOM LAUNCH THE TISSO FOREST

Trees are nature’s climate protectors: They produce oxygen, filter CO2 from the air, and use their roots to protect the soil from erosion. Together with Treedom, a global environmental organization, we’re planting new trees in Kenya, Nepal, and Colombia: With 300 fruit and timber trees in our own TISSO Forest, we offer small farmers in a region particularly affected by climate change and deforestation a guaranteed source of agricultural income—while simultaneously offsetting 68,000 kg of carbon dioxide. In the coming years, the TISSO Forest will continue to grow with our support.

Two hands holding soil with a young seedling
OUR VISION

A healthy life and well-being for all people.

OUR MISSION

We promote sustainable health through root-cause treatment based on natural ingredients. We use innovative approaches to raise awareness in society about taking personal responsibility for one’s lifestyle by sharing our expertise.

OUR VALUES

Specifically

OPTIMIZATION

Our work is always guided by our customers’ needs. We constantly ask ourselves whether we can improve what we do or come up with new approaches. Continuous optimization and improvement within the company are essential to ensuring our customers’ long-term satisfaction.

HUMANITY

We value a pleasant and social work environment and customer experience.

We always act with respect, appreciation, and tolerance. We treat customers, business partners, and employees exactly as we would like to be treated ourselves. We only make promises if we can keep them.

NATURALNESS

Preserving nature is a top priority for us.

We place the highest value on high-quality, natural raw materials.

We are authentic.

INNOVATION

We always keep an eye out for trends and developments.
In order to continually offer new and even better products, we are constantly acquiring new knowledge.

SYNERGY

Like our role model, nature, we use and combine resources as efficiently as possible to take full advantage of synergies.

We formulate our products so that the individual ingredients complement, support, and enhance one another in the best possible way. Similarly, our nutritional approach focuses on achieving the best possible synergistic effects through a combination of methods. We are always open to exploring new treatment approaches and creating additional synergies from them.

FLEXIBILITY

We always respond to our customers' needs with a focus on finding solutions. We take the initiative to deliver customized solutions on our own.
Flexibility speeds up our own projects and, in turn, strengthens our relationships with our customers.

THE RIGHT NUTRIENTS FOR YOUR PET: PROVICELL

Hello, animal lover! 
Why not treat your pet to something special, too—with the natural dietary supplements from our sister company, PROVICELL!
Many of our customers have always used our recipes for their pets, with excellent results. Based on the TISSO nutritional concept and in close collaboration with veterinarians and animal health practitioners, we have developed our own product line that is specifically tailored to the needs of animals.
For information and to order, visit PROVICELL

PROVICELL
PROVICELL ad: A dog and a cat are snuggling together, with the products EM Vital, Immun Vital, and Probiotic Vital in the foreground, accompanied by the text “Natural products for animal well-being”
PROVICELL ad: A dog and a cat are snuggling together, with the products EM Vital, Immun Vital, and Probiotic Vital in the foreground, accompanied by the text “Natural products for animal well-being”