Probiotics Gut Cure Original—Packaging for Pro EM san, Pro Mucosa, and Pro Präbioma
Pro Präbioma, Pro EM san, and Pro Mucosa; Features: proprietary bacterial strains, histamine-free, gluten-free
Easy to use, daily: Pro EM san: take it straight, with water, or with juice; Pro Präbioma: easily dissolves in tea or yogurt; Pro Mucosa: swallow as a capsule
What is Probiotics Gut Cure Original used for? Probiotics, soluble fiber, and mucosal nutrients for your gut health: builds up the gut flora, supports the skin and mucous membranes, and strengthens the immune system
vegan
lactose-free
gluten-free
yeast-free
hypoallergenic
Tested for harmful substances
of course
additive-free

Dietary supplements

Probiotics Gut Cure Original

4.8 (150)

The All-Inclusive Package for Your Gut—Including Pro EM san: Our probiotic gut health regimen combines three of our best products for your gut health. You’ll get everything your gut needs. Take advantage of this special package price now! 

  • Pro EM san, Pro Präbioma, and Pro Mucosa as a product bundle
  • Better value than buying individually—exclusively in this bundle
  • 31 probiotic strains plus 4 dietary fibers for healthy gut flora
  • Gut-healthy polyphenols from 24 fermented herbs and plants
  • Top nutrients for healthy mucous membranes and an intact gut barrier
  • Perfect for building up gut flora 
vegan
lactose-free
gluten-free
yeast-free
hypoallergenic
Tested for harmful substances
of course
additive-free
149,10 €
Tax included. Shipping calculated at checkout.
Product available—delivered to you in 1–4 daysin-house developmentown default position
Developed in collaboration with therapists

+8,000 doctors and alternative practitioners
See what the therapists have to say

PZN:19889358

The All-Inclusive Package for Your Gut: Our probiotic gut health regimen combines three of our best products for your gut health: Pro EM san, Pro Präbioma, and Pro Mucosa. You get everything your gut needs—and you’ll save money compared to buying them separately!

Health Claims

  • Calcium contributes to the normal function of digestive enzymes and to normal energy metabolism.
  • Zinc contributes to carbohydrate and fatty acid metabolism and to the functioning of the immune system.
  • The vitamins riboflavin (B2), niacin (B3), and biotin (B7) help maintain healthy mucous membranes.

The sudden intake of probiotics and dietary fiber can—especially in an unaccustomed or impaired digestive system—initially lead to symptoms such as a feeling of fullness or bloating. That is why we recommend a gradual introduction when taking our probiotic digestive treatment.

The following table is intended only as a guideline to help you achieve the best possible results while ensuring optimal tolerability. You can adjust the dosage schedule flexibly as needed, based on your individual tolerance and, if necessary, in consultation with your doctor or naturopath.

RECOMMENDED DOSAGE SCHEDULE

DAY 1 + DAY 2DAY 3 + DAY 4DAY 5 + DAY 6FROM DAY 7NOTES (Please refer to any additional information on the packaging.)
PRO EM SAN / PRO EM SAN PUR5 ml10 ml20 ml30 mlTake undiluted or mixed with still water or juice; preferably on an empty stomach, at least 30 minutes before a meal; can be divided into 1 to 3 doses per day
PRO PREBIOMA1/2 measuring spoon1 measuring spoon1 measuring spoon in the morning; 1/2 measuring spoon in the evening1 measuring spoon in the morning; 1 measuring spoon in the eveningTake with or without meals, stirred into still water, juice, or tea; dissolves particularly quickly in warm or hot beverages
PRO MUCOSA3 x 1 capsule3 x 2 capsules3 x 3 capsules3 x 4 capsulesTake with meals; can be divided into 1 to 3 individual doses per day


Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.  
Do not exceed the recommended daily intake.

Store in a cool, dry place away from light.

Keep out of the reach of small children.

Please leave the desiccant packet in the can. It contains food-grade silica gel and protects the product from moisture.

Special notes regarding Pro EM san:
Store at room temperature before opening; after opening, store in a cool place away from light at a maximum of 7 °C. Swirl the product before opening; do not shake. Once opened, use within approximately 1 month. Store in an upright position and do not drink directly from the bottle. Carbon dioxide buildup may cause slight overpressure in the bottle.

Ingredients per EMper daily dose
Bacterial culturesapprox. 3 × 10¹⁰ CFU*
Herbal and plant blend extract315 mg
Grapefruit seed extract4.9 µl
Ling Zhi (Reishi mushroom)20 mg
Grape seed extract20 mg
Cane sugar0.3 g
Sugar cane molasses0.4 ml
Pro EM san Nutritional Valuesper 100 mlper daily dose
Energy25 kJ/6 kcal8 kJ/2 kcal
Fat0 g0 g
of which saturated fatty acids0 g0 g
Carbohydrates1.5 g<0.5 g
of which sugars0.84 g0.25 g
Dietary fiber0.7 g0.2 g
Protein0 g0 g
Salt<0.01 g<0.01 g
*Colony-forming units
Pro Präbioma Ingredientsper daily dose%NRV*
Guar gum (partially hydrolyzed - Sunfiber®)4,000 mg-
Acacia fiber (dried milk sap from the trunk and branches of Acacia senegal)3,000 mg-
Resistant dextrin1,606 mg-
α-gluco-oligosaccharides (BioEcolians®)500 mg-
Calcium120 mg15
Zinc1.5 mg15
Pro Präbioma Nutritional Valuesper 100 gper 5 gper 10 g (daily dose)
Energy914 kJ/223 kcal46 kJ/11 kcal91 kJ/22 kcal
Fat<0.5 g<0.5 g<0.5 g
of which saturated fatty acids0 g0 g0 g
Carbohydrates16 g0.8 g1.6 g
of which sugars3.0 g<0.5 g<0.5 g
Dietary fiber68 g3.4 g6.8 g
Protein5.4 g0.25 g0.5 g
Salt0.35 g0.015 g0.03 g
*Percent of the Daily Reference Intake, according to the Food Information Regulation (LMIV)
Pro Mucosa Ingredientsper daily dose%NRV*
Sunflower lecithin1,500 mg-
L-glutamine1,200 mg-
Rice protein835 mg-
Hericium erinaceus (Yamabushitake)500 mg-
L-Alanyl-L-glutamine300 mg-
Methylsulfonylmethane (MSM)300 mg-
Broccoli extract100 mg-
Sophora japonica L. extract158 mg-
of which quercetin150 mg-
Resveratrol73.5 mg-
Fig tree sap powder50 mg-
Vitamin B3 (nicotinamide)8 mg50
Vitamin B2 (riboflavin)0.7 mg50
Vitamin B6 (pyridoxal-5'-phosphate)0.7 mg50
Biotin25 μg50
*Percent of the recommended daily intake, according to the Food Information Regulation (LMIV)

Ingredients:

According to EM san:
Water; mixture of sugars (sugarcane molasses, cane sugar, malt); sugarcane molasses; cane sugar; herbal and plant extracts (pineapple; angelica root; anise; basil; dill seeds; fennel; rosehip fruit; blueberry leaves; raspberry leaves; elderflower; ginger; olive leaves; oregano; peppermint; rosemary leaves; rooibos; red clover leaves; sage leaves; black cumin seeds; licorice; thyme; grapefruit seed extract; grape seed extract (OPC); Ling Zhi (reishi mushroom); microorganisms
Bacterial cultures contained (approx. 1 • 10¹¹ = 100,000,000,000 bacteria per 100 ml):
1. Bacillus subtilis
2. Bifidobacterium animalis subsp. animalis
3. Bifidobacterium bifidum
4. Bifidobacterium breve
5. Bifidobacterium longum subsp. longum
6. Bifidobacterium longum subsp. infantis
7. Bifidobacterium animalis subsp. lactis
8. Enterococcus lactis
9. Lactobacillus acidophilus
10. Lactobacillus amylolyticus
11. Lactobacillus amylovorus
12. Lactobacillus delbrueckii subsp. bulgaricus
13. Lacticaseibacillus casei 01
14. Lacticaseibacillus casei 02
15. Lacticaseibacillus casei 03
16. Lactobacillus crispatus
17. Lactobacillus delbrueckii
18. Lentilactobacillus farraginis
19. Lactobacillus gasseri
20. Lactobacillus helveticus
21. Lactobacillus johnsonii
22. Lacticaseibacillus paracasei
23. Lentilactobacillus parafarraginis
24. Lactiplantibacillus plantarum
25. Limosilactobacillus reuteri
26. Lacticaseibacillus rhamnosus
27. Ligilactobacillus salivarius
28. Lacticaseibacillus zeae
29. Lactococcus lactis biovar diacetylactis
30. Lactococcus lactis subsp. lactis
31. Streptococcus thermophilus
Contains licorice.
The sugarcane molasses and cane sugar are consumed by the microorganisms during the fermentation process and converted into lactic acid.
Since this is a naturally fermented product, cell counts may vary.
No flavor enhancers, preservatives, or artificial colors.

Pro Präbioma:
Thickening agents: guar gum (partially hydrolyzed - Sunfiber®) (40.0%); acacia fiber (dried milk sap from the trunk and branches of Acacia senegal) (30.0%); Resistant dextrin (16.1%); calcium L-pidolate (8.9%); α-gluco-oligosaccharides (BioEcolians®) (5.0%); zinc citrate trihydrate
Contains no flavor enhancers, preservatives, or artificial colors.

Pro Mucosa:
L-Glutamine; Coating Agent: DR Hydroxypropylmethylcellulose; Rice Protein; Hericium erinaceus (Yamabushitake); L-Alanyl-L-Glutamine (4.9%); Methylsulfonylmethane (MSM) (4.9%); Quercetin (2.4%); Broccoli extract (1.6%); Resveratrol extract; Vitamin B3 (nicotinamide); Vitamin B2 (riboflavin); Vitamin B6 (pyridoxal-5'-phosphate); D-biotin; Stabilizer: sunflower lecithin (24.3%); Sophora japonica L. extract (quercetin) (2.4%); Polygonum cuspidatum extract (resveratrol); fig tree sap powder
No flavor enhancers, preservatives, or artificial colors.

Your legal guarantee rights
LEGAL GUARANTEE Minimum two-year legal guarantee protection for goods sold in the European Union. Consumers can claim their rights under the legal guarantee of conformity, for example if goods: do not match the description; do not function as intended. Sellers are liable for any lack of conformity which existed when the goods were delivered, and which becomes apparent within the legal guarantee period. Sellers in such a situation are required to offer: free repair or free replacement; in some cases, a price reduction or full reimbursement. Some countries have a longer legal guarantee period. For second-hand goods, a shorter period may apply, but not less than one year. For more information on your rights in a specific country, scan the QR code below or ask the seller. europa.eu/youreurope/guarantees What to do if you receive non-conforming goods: 1 Contact the seller as soon as possible to report the issue; 2 Provide proof of purchase, such as a receipt, invoice, or bank statement. Sellers and producers may also offer commercial guarantees, which apply independently from the legal guarantee. For example, you may see this GARAN label representing a commercial guarantee of durability offered by the producer at no additional cost and covering the entire good.

Open the legal guarantee notice on Your Europe

NATURE AND RESEARCH EFFECTIVELY COMBINED
From practice for people.
NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH
Frau mit Hand auf Bauch
Frau mit Hand auf Bauch

Restoring Gut Flora with Probiotics and Fiber

A healthy body needs a healthy gut. And a healthy gut needs a healthy gut flora—which means, above all, one that is diverse and rich in species. Pro EM san Supports the development of your gut flora with 31 probiotic bacterial cultures—all quality-controlled and sourced from our in-house culture collection. In addition, the included fermented herbal and plant extract provides an abundance of polyphenols that benefit both you and the bacteria in your gut.

Our Fiber Blend Pro Präbioma It also provides your healthy gut bacteria with their most important source of nutrition, thereby promoting their growth and activity. Our four types of dietary fiber are formulated to optimally meet the varied preferences of your little friends and are also fermented slowly. The latter prevents excessive gas formation in the gut, making it particularly easy to digest.

Prefer fewer herbs? Probiotic Gut Cleanse (Unflavored)
If you're not a fan of herbs, just try our Probiotics Gut Cure Pur. The alternative package contains, instead of Pro EM san our version with fewer herbs Pro EM, pure and simple.

Wasser in Sandrillen
Wasser in Sandrillen

Nutrients and Energy for Your Mucous Membranes

A healthy gut also requires a healthy intestinal mucosa. The mucous membranes in your body are among the first and most important internal protective barriers against pathogens and harmful substances. The intestinal lining—which, with a surface area of about 500 m², is the largest of your mucous membranes—also houses a large portion of your immune cells, ensures the absorption of nutrients from food, and serves as a home and breeding ground for your gut bacteria.

Mucosal cells are constantly renewing themselves and therefore require plenty of energy and nutrients. That is why our probiotic gut treatment also contains Pro Mucosa. This nutrient complex provides your mucous membranes with essential building blocks (phosphatidylcholine) from high-quality sunflower lecithin, nourishing plant extracts, and their most important source of energy, the amino acid L-glutamine. In addition, vitamins B2, B3, and biotin keep your mucous membranes fit and healthy.

ALSO AVAILABLE IN THIS VERSION FROM US

Probiotics Gut Cure Pur—Packaging for Pro EM san pur, Pro Mucosa, and Pro Präbioma
Pro EM san pur, Pro Präbioma, and Pro Mucosa; Features: proprietary bacterial strains, histamine-free, gluten-free
Probiotics Gut Cure Pur
4.6 (34)
Your all-in-one package for gut health, gut flora, and healthy mucous membranes. Monthly package with Pro EM san pur, Pro Präbioma, and Pro Mucosa. Includes a package discount.
149,10 € Includes sales tax; shipping not included

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also truly worth highlighting is that the products are based on the latest scientific findings and take into account our own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO's highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports the health of my patients.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from alternative practitioners for alternative practitioners, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, alternative practitioner
Potsdam


“I’ve been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results.”

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, naturopath
Trier


“As a naturopath, I specifically apply the TISSO approach to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic therapy approaches and fully meet my high standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel


“I absolutely love working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I really appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

The TISSO Original Probiotic Intestinal Treatment is a proven 3-phase approach to holistic intestinal detoxification. It was developed based on many years of experience to help you To specifically build up, strengthen, and sustainably stabilize the gut flora – especially after taking antibiotics, when experiencing digestive problems, or when the immune system is weakened.
The treatment regimen combines three products that are perfectly coordinated:

  • Pro EM san – liquid multispecies probiotic with live bacterial cultures
  • Pro Präbioma – prebiotic fiber powder designed to specifically promote beneficial gut bacteria and strengthen the intestinal lining
  • Pro Mucosa – an optimal combination of nutrients for the regeneration of the intestinal mucosa

This holistic approach supports the restoration of healthy gut flora and the strengthening of the intestinal barrier, including the immune system—and thus also your well-being from the inside out.

The Probiotics Gut Cure Original combines:

  • 31 probiotic bacterial cultures (e.g., Lactobacillus, Bifidobacterium)
  • Soluble fiber as a breeding ground for a healthy microbiome and to strengthen the intestinal mucosa
  • Plant-Based Polyphenols Made from grape seeds, olive leaves, and more to support microbiome diversity—a total of 24 herbal and plant extracts
  • Glutamine, lecithin, MSM, B vitamins, and bioactive plant compounds for the regeneration of the intestinal mucosa

This combination of Probiotics, Prebiotics, and Mucosal Nutrients Works synergistically—to promote a stable, diverse, and resilient microbiome; a healthy intestinal barrier; and healthy digestion.

The Original Probiotic Gut Health Program combines three complementary products that work together to strengthen your gut flora, regenerate the mucous membrane, improve digestion, and boost your immune system. It also has a positive effect on your skin, brain, and liver, for example.

Pro EM san provides live, active bacterial cultures that help restore balance to the microbiome and thus ward off harmful bacteria.

Pro Präbioma provides beneficial gut bacteria with soluble fiber, thereby promoting their growth and strengthening the intestinal lining at the same time.

Pro Mucosa Supports the regeneration of the intestinal mucosa and strengthens the intestinal barrier—thanks to selected nutrients such as glutamine, lecithin, selected plant-based nutrients, MSM, and B vitamins.

The treatment begins on Day 1 with all three products and is gradually increased to improve tolerability:

  • According to EM san: Start with 5 ml daily and increase the dose every two days to 10 ml, then 20 ml, and starting on day 7, to 30 ml—it’s best to take it on an empty stomach, either straight or mixed with still water or juice.
  • Pro Präbioma: Start with ½ measuring spoon daily, increase to 1 measuring spoon, then to 1 measuring spoon in the morning and ½ measuring spoon in the evening. Starting on day 7: stir 1 measuring spoon into water, tea, or juice in the morning and another 1 measuring spoon in the evening. It dissolves especially well when warm.
  • Pro Mucosa: Start by taking 1 capsule 3 times a day with meals, and gradually increase the number of capsules until you reach 4 capsules 3 times a day starting on day 7.

Important: Drink plenty of fluids (at least 2 liters a day)—and the dosage can be adjusted individually if necessary.

The Probiotics Gut Cure Original is suitable for anyone who wants to Targeted Rebuilding of Gut Flora and her Strengthen Digestion for the Long Term would like to. It is especially recommended for:

  • Digestive problems such as bloating, diarrhea, or constipation
  • one compromised gut flora following antibiotic treatment
  • increased intestinal permeability (leaky gut syndrome)
  • Food Intolerances or a sensitive digestive system
  • one weakened immune system
  • Skin problems

Most people tolerate the colon cleanse well. However, during the first few days of use, mild symptoms such as bloating, diarrhea, or mild abdominal cramps may occur as the intestines adjust to the ingredients. You can prevent side effects by gradually increasing the dose and monitoring how your body reacts.

Just give us a call, Send us an email at info@tisso.de Or send us your question using our contact form. You can reach us here.

CUSTOMER REVIEWS

4.8
Based on 150 reviews

Paula

Verified Reviewer

I recommend this product
I really like the 3-in-1 combo. Especially the Pro EM SAN. It is quick to take in a glass of warm water in the morning and shows effects quite quickly. In combination with the other 2 products, it is a very good combo for gut support.

Harald Riegler

Verified Buyer

I recommend this product
Significant improvement while on a fructose diet

Birgit Pellowski

Verified Buyer

I recommend this product
After only a short intake, a change in the gut was already noticeable. Very positive. Digestion already seemed different, and my own energy gradually returned. I would like to continue taking the product. It is currently helping me with the intake during a long-term prophylaxis of antibiotics (injection) for more than 6 months.

Heike Pühlhorn

Verified Buyer

I recommend this product
Highly recommended

Silke

Verified Buyer

I recommend this product
The product is good.

Corina Fürst

Verified Buyer

I recommend this product
Helps a lot with intestinal issues.

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND
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Probiotics
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