Pro GlutNzym, 30-capsule bottle; features: vegan, capsule, TISSO Study
Pro GlutNzym bottle; Features: lactose-free, gluten-free, fructose-free, yeast-free
Pro GlutNzym is easy to use: 1 capsule daily. A tip for swallowing—the “nod trick”: 1. Place the capsule on your tongue, 2. Take a sip of water, 3. Tuck your chin toward your chest, 4. Swallow
What sets Pro GlutNzym apart? High-quality branded raw material IN VIVO BIOTICS™ gluten tolerance, 7 bacterial strains and their lysates, supplemented with Bacillus protease – conventional product: often standard formulations, only live bacteria without lysates, usually without additional enzymes
vegan
fructose-free
lactose-free
gluten-free
yeast-free
Tested for harmful substances
additive-free

DIETARY SUPPLEMENTS

Pro GlutNzym

To support the digestion of gluten-containing meals , itcontains IN VIVO BIOTICS™ gluten tolerance, a carefully formulated combination of bacterial strains, enzymes derived from their lysates, and an additional specific enzyme.

  • IN VIVO BIOTICS™ gluten tolerance – Bacterial Strains and Enzymes
  • 7 bacterial strains – 3 billion colony-forming units per daily dose
  • Lysates from bacterial strains that contain enzymes in particular
  • Bacillus protease—an enzyme derived from microbial fermentation
  • to support, in particular, a low-gluten diet
vegan
fructose-free
lactose-free
gluten-free
yeast-free
Tested for harmful substances
additive-free

46,95 €

Choose your volume discount:

Volume discounts cannot be combined with subscription plans.

46,95 €

Content: 15 g | 1 kg = 3.130,00 €
Tax included and shipping calculated at checkout

46,95 € 44,60 €

Product available—delivered to you in 1–4 daysfrom 1,57 € per dayCapsules: 15 g = 30 capsulesAvailable through a savings planTISSO Study
Developed in collaboration with therapists

+8,000 doctors and alternative practitioners
See what the therapists have to say

PZN:

Whether you're on the go, traveling, or eating out—it's not always possible to avoid consuming gluten. Pro GlutNzym combines selected bacterial strains, whose enzymes (lysates) and Bacillus protease help support the digestion of gluten-containing meals.

It is recommended to take 1 capsule daily with plenty of liquid. It may be taken with or without a meal.
Do not exceed the recommended daily intake.

Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.
Store in a cool, dry place away from light.
Keep out of the reach of small children.
Please leave the desiccant packets in the cans until the product is used up. They contain food-grade silica (silicon dioxide) and protect the product by absorbing moisture that enters the can every time it is opened. This keeps the product dry.

Special Notes:
Not suitable for pregnant or breastfeeding women.

This is not a substitute for a gluten-free diet.

Store in the refrigerator before opening for the first time. After opening, store at room temperature in a dry place away from light, and use within 3 months.

Ingredientsper daily dose
IN VIVO BIOTICS™ gluten tolerance450 mg
of which bacterial strains:3 x 10⁹ CFU¹
Lactobacillus species2 x 10⁹ CFU
Bacillus species1 × 10⁹ CFU
of which bacterial strain lysates:3 × 10⁹ CFU²
Lactobacillus species2 × 10⁹ CFU
Bacillus species1 × 10⁹ CFU
of which Bacillus protease: 10 mg
¹Colony-forming units (total bacterial count of at least 3 × 10⁹ CFU until the end of the best-before date)
²Lysates are derived from these quantities of colony-forming units

Ingredients:

Bacterial strains and their lysates: Lactiplantibacillus plantarum DSM 33363, Lactiplantibacillus plantarum DSM 33364, Lacticaseibacillus paracasei DSM 33373, Limosilactobacillus reuteri DSM 33374, Bacillus pumilus DSM 33297, Bacillus pumilus DSM 33355, Priestia megaterium DSM 33300; Coating agent: hydroxypropyl methylcellulose (capsule shell); Bacillus protease

No flavor enhancers, preservatives, or artificial colors.

Pollutant analyses conducted by independent laboratories

Quality and safety are TISSO's top priorities. That is why we have our products tested regularly by independent laboratories. 

The contaminant analyses we conduct ensure that our products consistently meet the highest quality standards. To Pro GlutNzym The test results from a DAkkS-accredited laboratory are available for you to download.

Download Analysis Confirmation

Download Test Report

Your legal guarantee rights
LEGAL GUARANTEE Minimum two-year legal guarantee protection for goods sold in the European Union. Consumers can claim their rights under the legal guarantee of conformity, for example if goods: do not match the description; do not function as intended. Sellers are liable for any lack of conformity which existed when the goods were delivered, and which becomes apparent within the legal guarantee period. Sellers in such a situation are required to offer: free repair or free replacement; in some cases, a price reduction or full reimbursement. Some countries have a longer legal guarantee period. For second-hand goods, a shorter period may apply, but not less than one year. For more information on your rights in a specific country, scan the QR code below or ask the seller. europa.eu/youreurope/guarantees What to do if you receive non-conforming goods: 1 Contact the seller as soon as possible to report the issue; 2 Provide proof of purchase, such as a receipt, invoice, or bank statement. Sellers and producers may also offer commercial guarantees, which apply independently from the legal guarantee. For example, you may see this GARAN label representing a commercial guarantee of durability offered by the producer at no additional cost and covering the entire good.

Open the legal guarantee notice on Your Europe

NATURE AND RESEARCH EFFECTIVELY COMBINED
From practice for people.
NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH
Eine lächelnde Frau mit lockigem Haar sitzt in einem Café an einem Tisch und isst mit einem Löffel ein Dessert aus einem Glas, neben einer Tasse Cappuccino.
Eine lächelnde Frau mit lockigem Haar sitzt in einem Café an einem Tisch und isst mit einem Löffel ein Dessert aus einem Glas, neben einer Tasse Cappuccino.

Bacterial Strains, Lysates, and Bacillus Protease—A Unique Combination

Each serving of GlutNzym contains the proprietary ingredient IN VIVO BIOTICS™ gluten tolerance. The formula combines seven selected bacterial strains made from Lactobacillus and Bacillus species, with a total of 3 billion colony-forming units (CFU) per daily dose. These help replenish the gut flora with proven bacterial cultures.

A special feature of the formula is the inclusion of Lysates of these bacterial strains. Lysates are produced by specifically breaking down the cell walls of the microorganisms. This preserves the bacteria's natural components—including above all, proven enzymes and other characteristic components of the microorganisms. The formulation is supplemented by the Bacillus protease, An enzyme produced by microbial fermentation.

These enzymes can break down proteins—such as gluten—into smaller components. They are a natural part of the digestive process and are responsible for gradually breaking down complex protein structures.

The combination of selected bacterial strains—and, above all, their enzymes (lysates)—and Bacillus protease distinguishes IN VIVO BIOTICS™ Gluten Tolerance from many traditional enzyme products, which generally do not contain live cultures to support the microbiome.

Goldgelbe Weizenkörner liegen verstreut auf einer Holzfläche, zusammen mit einem gefüllten Jutesack, einer Holzschaufel und getrockneten Weizenähren.
Goldgelbe Weizenkörner liegen verstreut auf einer Holzfläche, zusammen mit einem gefüllten Jutesack, einer Holzschaufel und getrockneten Weizenähren.

Gluten—a protein with a unique structure

Gluten is one of the proteins with a particularly complex structure. Unlike other proteins, it is not completely broken down by the body's own enzymes, so that larger protein fragments remain. These can affect nearly all vital processes in the body.

For this reason, scientists and researchers have been studying for many years how gluten components can be further broken down. Scientific research is focused on both specific enzymes and microorganisms and their natural components (especially enzymes).

This is precisely where the concept of IN VIVO BIOTICS™ Gluten Tolerance . The formulation combines seven selected bacterial strains, their lysates, and Bacillus protease. The bacterial strains and their natural cellular components form the basis of the formulation and are supplemented by Bacillus protease.

Thus, it combines Pro GlutNzym Various ingredients of microbial origin in a specially formulated blend for use in conjunction with meals containing gluten.

Sources

1 Dunaevsky, Y. E., et al. (2021). Effective degradation of gluten and its fragments by gluten-specific peptidases: A review of their application in the treatment of patients with gluten sensitivity. Pharmaceutics, 13(10), 1603. https://doi.org/10.3390/pharmaceutics13101603

2 Francavilla, R., et al. (2017). Selected probiotic lactobacilli have the capacity to hydrolyze gluten peptides during simulated gastrointestinal digestion. Applied and Environmental Microbiology, 83(14), e00376-17. https://doi.org/10.1128/AEM.00376-17

3 Nikoloudaki, O., et al. (2024). Novel probiotic preparation with in vivo gluten-degrading activity and potential modulatory effects on the gut microbiota. Preprint, June 2024. https://www.researchgate.net/publication/381319929_Novel_probiotic_preparation_with_in_vivo_gluten-degrading_activity_and_potential_modulatory_effects_on_the_gut_microbiota

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also worth highlighting is that the products are based on the latest scientific findings and take into account the company’s own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO’s highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports my patients’ health.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from naturopaths for naturopaths, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it to others!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, Alternative Medicine Practitioner
Potsdam


"I've been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results."

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, alternative medicine practitioner
Trier


“As a naturopath, I apply the TISSO approach specifically to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic treatment approaches and fully meet my standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel


"I really enjoy working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

Pro GlutNzym is a dietary supplement containing the proprietary ingredient IN VIVO BIOTICS™ gluten tolerance. It contains seven selected bacterial strains, their lysates, and the enzyme Bacillus protease, and can be a trusted companion for meals containing gluten.

Each serving of GlutNzym contains the proprietary ingredient IN VIVO BIOTICS™ gluten tolerance. The formula combines seven selected bacterial strains totaling 3 billion colony-forming units (CFU), their natural lysates, and Bacillus protease, an enzyme derived from microbial fermentation.

Pro GlutNzym was developed to support a healthy lifestyle, particularly for those following a low-gluten diet. It combines Bacillus protease with selected bacterial strains and their lysates, thereby bringing together various components of microbial origin in a single capsule.

It is recommended to take 1 capsule daily with plenty of liquid. It can be taken with or without a meal and can be easily incorporated into your daily routine.

Bacterial lysates are components of microorganisms produced by the targeted disruption of cell walls. In this process, natural structures such as enzymes, cellular components, and other elements are preserved, although the lysates do not contain living cells. They are specifically used to harness certain properties of the original bacteria even though these bacteria are no longer capable of reproducing.

Live bacteria are microorganisms capable of reproduction that can be active in the gut. Lysates, on the other hand, consist of processed components of these bacteria but no longer contain any live cells. While live bacteria are valued for their activity, lysates provide structural, biologically active components of the microorganisms. In some products, such as Pro GlutNzym, this combination has proven effective.

It can be taken with or without a meal. It is also a good idea to take it shortly before or with a meal that may contain gluten.

Yes, Pro GlutNzym contains selected bacterial strains totaling 3 billion colony-forming units (CFU) per daily dose.

No, Pro GlutNzym is not a substitute for a gluten-free diet. The product is intended as a supplement to help manage meals containing gluten and is designed for people who want to make conscious choices about their diet.

Yes. If you don't want to swallow the capsules, you can open them and stir the powder into still water, unsweetened herbal teas, or even foods such as granola, yogurt, or applesauce. (Please do not add it to hot drinks or foods!) Consume immediately after opening.

Just give us a call, Send us an email at info@tisso.de Or send us your question using our contact form. You can reach us here.

CUSTOMER REVIEWS

4.8
Based on 4348 reviews

Laura Drexler

Verified Buyer

I recommend this product
Really good!
Really good!

Isabella Wedenig

Verified Reviewer

I recommend this product
Working with nature...free from laboratories and manipulations...may the goal remain quality.
The ingredients, herbal composition, selection, very harmonious, genuine, you can still taste the herb itself. Helps immediately, noticeably. Serious and clear processing when ordering, processed with a consciousness for nature right into the hands of the customer. Pro Intest..

Margrit

Verified Reviewer

I recommend this product
Order Processing
Order processing, shipping, and product Pro Mucosa all 100 % 👍👍☺️

Siegfried

Verified Reviewer

I recommend this product
Everything is great
Everything is great, quality, price, performance

Michela Ciuffreda

Verified Buyer

I recommend this product
Maximum precision thanks to Italy
Maximum precision thanks to Italy

Aneta Wozny

Verified Buyer

I recommend this product
Super Product
Super product! Fast delivery

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND
Nahaufnahme der Hände einer Person, die auf einem Holzschneidebrett mit einem Küchenmesser eine frische Ananas in Scheiben schneidet; Bildhinweis: KI-gestützter Inhalt
Product Category
Enzymes
Nahaufnahme eines Bauchs mit Bauchnabel
Scope of Application
Intestines & Digestion
Hands are passing a plate of sandwiches
Blog
Gluten Intolerance: Improving Well-Being Through Mindful Eating