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What is celiac disease, and what’s the best way to live with it?

December 18, 2025Timo HarbeckeReading time: 3,5 Minuten

Celiac disease is much more than a simple gluten intolerance—it is a chronic autoimmune disorder in which the immune system reacts to gluten, a protein found in wheat, spelt, barley, and rye. This leads to inflammation and damage to the lining of the small intestine, which ultimately impairs nutrient absorption. The symptoms are varied and range from bloating, diarrhea, and abdominal pain to fatigue, skin problems, or unexplained weight changes.

Because celiac disease can cause a wide variety of symptoms, it often goes undiagnosed for a long time and frequently has a significant impact on well-being and quality of life. This makes early diagnosis and a consistent dietary change all the more important in order to relieve the intestinal mucosa and to improve and maintain quality of life in the long term. However, these measures should not obscure the fact that celiac disease cannot be completely cured. 

In this article, you'll learn how celiac disease is diagnosed, which foods are suitable, what role dietary supplements can play, and how you can stay active, productive, and largely healthy despite your diagnosis.

How can celiac disease be diagnosed?

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Accurately diagnosing celiac disease is crucial for properly identifying symptoms and preventing potential long-term damage. The first medical step is a blood test that screens for specific antibodies, which are often elevated in celiac disease (e.g., transglutaminase antibodies). If these levels are abnormal, a small intestine biopsy is performed during a colonoscopy to confirm the diagnosis . Only through this tissue examination can it be determined whether the small intestinal mucosa has already undergone inflammatory changes or has become flattened—a clear sign of celiac disease.

Distinction from Gluten Intolerance
Because the symptoms can be similar, celiac disease is often confused with non-celiac gluten sensitivity (NCGS). The key difference:

  • Celiac disease is an autoimmune disorder characterized by detectable antibodies and damage to the intestinal mucosa.
  • Non-celiac gluten sensitivity (NCGS) is characterized by the absence of antibodies and mucosal changes; the diagnosis is made through a process of elimination and by monitoring symptoms while following a gluten-free diet.

To ensure that blood test results and biopsy findings can be reliably evaluated, you should not switch to a gluten-free diet before undergoing diagnostic testing . Doing so could skew the results and make diagnosis more difficult.

What can you eat if you have celiac disease?

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A lifelong gluten-free diet is the only effective treatment for celiac disease, but it offers more variety than many people initially expect. Natural, gluten-free alternatives such as rice, corn, quinoa, buckwheat, and amaranth are versatile and support a balanced diet. Fruits, vegetables, legumes, meat, fish, eggs, tofu, tempeh, and dairy products are also safe and gluten-free.

You must avoid all foods containing wheat, barley, rye, spelt, and related varieties, since even small amounts of gluten can damage the mucous membrane again.
You should pay special attention to hidden gluten in processed foods—for example, in spice blends, ready-made sauces, breaded products, or baked goods. Certified gluten-free foods provide a good guide and make it easier to choose the right options in your daily life. It’s also important to prevent cross-contamination—even the tiniest traces of gluten on toasters, cutting boards, or knives can trigger symptoms.

Gluten-Free Options at a Glance:

  • Grains & Alternatives: Rice , Corn, Quinoa, Buckwheat, Amaranth 
  • Sources of protein: meat, fish, eggs, tofu/tempeh
  • Dairy products: milk, yogurt, cheese
  • Snacks: Nuts, seeds, kernels

What role do dietary supplements play in celiac disease?

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People with celiac disease often have a particularly sensitive digestive system. Damage to the intestinal lining limits the absorption of important nutrients. These include vitamins, minerals, and trace elements, which —along with a gluten-free diet—are crucial for energy metabolism, the immune system, and overall well-being. Dietary supplements can provide support in this regard and help restore the natural balance in the gut.

TISSO offers a range of high-quality products specifically tailored to the needs of a sensitive digestive system and designed to support the microbiome and the intestinal mucosa. The Original Probiotic Intestinal Treatment is a complete package consisting of probiotic bacterial cultures, soluble dietary fiber, and nutrients for the intestinal mucosa. It includes three products:

  • Each serving of EM contains 31 bacterial cultures with 24 fermented herbal and plant extracts to build and stabilize the gut microbiome.
  • Each serving of Präbioma contains soluble dietary fiber, which acts as “food” for beneficial gut bacteria, as well as calcium, which, among other things, supports the function of digestive enzymes.
  • With its special combination of nutrients, Pro Mucosa supports immune function and the regeneration of the intestinal mucosa.

How does celiac disease affect sports?

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Celiac disease can significantly affect athletic performance, as the condition directly impacts energy production and recovery . Damage to the intestinal lining can lead to impaired nutrient absorption, which, over the long term, results in deficiencies in essential vitamins and minerals. Iron and B vitamins are particularly critical, as they play a key role in energy production, oxygen transport, and muscle recovery. A deficiency can manifest as fatigue, reduced endurance, a drop in performance, or a prolonged recovery period after physical exertion.

To remain active and perform at your best despite celiac disease, a well-planned diet and an adequate intake of nutrients are particularly important. A balanced gluten-free diet forms the foundation and should be supplemented, if necessary, with carefully selected dietary supplements to compensate for potential deficiencies. In addition, regular checkups are recommended so that nutrient deficiencies can be detected early and addressed. With a conscious selection of foods, a consistent supply of nutrients, and a personalized supplementation regimen, athletic performance can be effectively maintained.

Conclusion: A Fulfilling Life with Celiac Disease

While living with celiac disease requires a permanent change in diet, with the right knowledge and well-planned routines, daily life can not only be managed but often made significantly easier. A strict gluten-free diet protects the intestinal lining, promotes its regeneration, and ensures that the body can once again absorb nutrients more effectively.
Regular checkups and a targeted intake of essential vitamins and minerals provide added peace of mind. The stability of the gut microbiome can also play a role: A combination of probiotics, prebiotics, and nutrients that support the mucous membranes—such as those found in the Probiotics Gut Care Original —can provide valuable support for the gut during sensitive periods.

As you gain more experience, living a gluten-free lifestyle becomes easier and easier. If you manage your condition carefully, you can lead an active, enjoyable, and energetic life in the long run—at work, in sports, and in your social life.

Sources

  • German Celiac Society (DZG). (June 11, 2025). Celiac Disease – Information for Those Affected and Professionals. https://www.dzg-online.de/  

FREQUENTLY ASKED QUESTIONS

The Symptoms of Celiac Disease Symptoms can vary widely. Common early signs include digestive problems such as bloating, diarrhea, abdominal pain, or a persistent feeling of fullness. Fatigue, nutrient deficiencies, weight loss, or skin changes may also occur. In children, growth delays sometimes occur. Anyone who notices such symptoms should seek medical advice to rule out the possibility of celiac disease.

If celiac disease is suspected, the first step is a Blood test, to detect specific antibodies. If the result is abnormal, this is followed by a Small intestine biopsy, that allows for a clear diagnosis. A Non-Celiac Gluten Sensitivity (NCGS) However, it cannot be confirmed by laboratory tests. It is diagnosed by ruling out other causes and observing that the symptoms improve with a gluten-free diet.

The damaged small intestine lining makes it harder to absorb certain nutrients. Vitamin D3, iron, calcium, and B vitamins are often affected. Also, the Gut microbiome plays an important role in celiac disease because it affects digestion and the intestinal mucosal environment. During periods when the gut is particularly sensitive or the mucosal lining is recovering, a combination of probiotics, prebiotics, and nutrients that support the mucosal lining may be beneficial. A tailored solution such as the Probiotics Gut Cure Original can help support the intestines during these phases.

Natural gluten-free foods include, for example, fruits, vegetables, meat, fish, eggs, legumes, and traditional dairy products. Also Pseudo-grains such as quinoa, buckwheat, or amaranth are ideal as the basis of a gluten-free diet. You must avoid all products containing wheat, barley, rye, and spelt, as well as foods that may contain hidden gluten—such as ready-made sauces, baked goods, or spice blends. Certified gluten-free products offer added assurance.

Untreated celiac disease can increase the risk of complications such as miscarriages, preterm births, or low birth weight—usually due to nutrient deficiencies. A confirmed diagnosis and a strictly gluten-free diet significantly reduce this risk. Pregnant women with celiac disease should Have nutrient levels checked regularly and maintain close contact with healthcare professionals.

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