Dietary supplements

Cycle Balance Package

Naturally balanced—every month: With vitamin B6 to regulate hormone activity. Plus proven plant-based ingredients, PEA, vitamins, minerals, and probiotics. Get this value-packed bundle now!

  • In the bundle: Pro Biom Anti-Stress, Pro PMS Balance, and Pro PEA 800
  • Better value than buying individually—exclusively in this bundle
  • Monk’s pepper, ginger, and saffron, as well as three selected bacterial cultures
  • Bioidentical palmitoylethanolamide (PEA)—highly concentrated
  • Vitamin B6 to regulate hormonal activity 
  • Biotin, magnesium, and copper—for the nervous system and energy metabolism
  • Zinc—for cognitive function, cell protection, and fertility
vegan
fructose-free
lactose-free
gluten-free
yeast-free
Tested for harmful substances
of course
additive-free
Price: 84,91 €
Tax included. Shipping calculated at checkout.
Product available—delivered to you in 1–4 daysin-house development
Developed in collaboration with therapists

+8,000 doctors and alternative practitioners
See what the therapists have to say

PZN:

Naturally in balance—every month: With vitamin B6 to help regulate hormone activity. Plus proven plant extracts, PEA, vitamins, minerals, and bacterial cultures. Take advantage of this special package deal now!

Health Claims

  • Biotin contributes to the normal functioning of the mind and nervous system, as well as to the maintenance of mucous membranes and healthy energy metabolism.
  • Magnesium contributes to healthy muscle function and normal energy metabolism, and helps reduce tiredness and fatigue.
  • Zinc supports normal fertility and reproduction and helps protect cells from oxidative stress.
  • Copper is essential for healthy energy metabolism and supports iron transport in the body.
  • Vitamin B6 helps regulate hormone activity, supports healthy energy metabolism, promotes healthy mental function and nervous system function, and helps reduce tiredness and fatigue.

PRODUCTDOSAGERECOMMENDED SERVING SIZE (Please refer to any additional information on the packaging)
PRO PMS BALANCE3 capsulesTake with plenty of liquid in the morning with a meal or spread out over several meals
PRO BIOM ANTI-STRESS1 capsuleTake with plenty of liquid during or after a meal
PRO PEA 8002 capsulesTake with plenty of liquid with a meal


Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.  
Do not exceed the recommended daily intake.

Store in a cool, dry place away from light.

Keep out of the reach of small children.

Please leave the desiccant packet in the can. It contains food-grade silica gel and protects the product from moisture.

Special Notes:

Pro PMS Balance
Not suitable for pregnant women, nursing mothers, or children. If you are taking prescription blood thinners, it is recommended that you consult your prescribing physician beforehand.

Pro Biom Anti-Stress
Not suitable for pregnant or breastfeeding women or individuals under the age of 18. Do not consume with other dietary supplements containing saffron.

Pro Biom Anti-Stress Ingredientsper daily dose%NRV*
Bacterial cultures5 x 10⁹ CFU¹-
CEREBIOME®: Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-1753 x 10⁹ CFU¹-
Lactobacillus rhamnosus GG2 x 10⁹ CFU¹-
Saffron extract (Safr’Inside™)30 mg-
Biotin7.5 µg15
*Percent of the Daily Reference Intake (DRI), according to the Food Information Regulation (LMIV)
¹colony-forming units (total bacterial count of at least 5 x 10⁹ CFU until the end of the best-before date)
CEREBIOME® is a registered trademark of Danstar Ferment AG.
Safr’Inside™ is a registered trademark of Activ’inside.
Pro PMS Balance Ingredientsper daily dose%NRV*
Ginger extract260 mg-
of which gingerols52 mg-
Monk’s pepper extract20 mg-
Zinc10 mg100
Copper0.5 mg50
Magnesium130 mg34.7
from magnesium bisglycinate50 mg-
from magnesium malate80 mg-
Vitamin B6 (pyridoxal-5'-phosphate)1.4 mg100
*Percent of the recommended daily intake, according to the Food Information Regulation (LMIV)
Pro PEA 800 Ingredientsper daily dose
Palmitoylethanolamide (PEA)800 mg

Ingredients:

Pro Biom Anti-Stress:
Potato starch; Coating agent: hydroxypropyl methylcellulose; Lactobacillus helveticus Rosell®-52; Bifidobacterium longum Rosell®-175; Lactobacillus rhamnosus GG; Saffron extract (Crocus sativus L.); bulking agent: gum arabic (acacia fiber); antioxidant: L-ascorbic acid; biotin
No flavor enhancers, preservatives, or artificial colors.

Pro PMS Balance:
Magnesium malate; magnesium bisglycinate; coating agent: hydroxypropyl methylcellulose; ginger extract (15.5%); bulking agent: gum arabic (acacia fiber); Zinc gluconate; anti-caking agent: ascorbyl palmitate; monk’s pepper extract; pyridoxal-5'-phosphate (0.1%); copper bisglycinate
No flavor enhancers, preservatives, or artificial colors.

Pro PEA 800:
Palmitoylethanolamide; Pullulan
No flavor enhancers, preservatives, or artificial colors.

NATURE AND RESEARCH EFFECTIVELY COMBINED
From practice for people.
NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH
Frau entspannt auf dem Sofa mit Tee – natürliche Unterstützung bei PMS
Frau entspannt auf dem Sofa mit Tee – natürliche Unterstützung bei PMS

Herbal Remedies for PMS, Menstrual Cramps, and Dysmenorrhea

The menstrual cycle consists of distinct phases that repeat every month. Hormones play a role in this process. The Cycle Balance Package combines numerous ingredients, including essential vitamins and minerals:

  • Vitamin B6 helps regulate hormonal activity.
  • Biotin as well as Magnesium and Vitamin B6 support the healthy functioning of the nervous system and the mind.
  • Magnesium is important for healthy muscle function and, just like Vitamin B6, biotin, and copper for normal energy metabolism.
  • Zinc contributes to normal fertility and reproduction, as well as to the protection of cells from oxidative stress.
  • Copper supports normal iron transport in the body.

In addition, the Cycle Balance Package contains proven plant-based ingredients such as Monk's pepper, ginger and Saffron, that have been used traditionally for a long time. With CEREBIOME®, a premium combination of two carefully selected Bacterial cultures (Lactobacillus helveticus RosellⓇ-52 and Bifidobacterium longum RosellⓇ-175) as well as the bacterial strain Lactobacillus rhamnosus GG and, in addition, the bioidentical Palmitoylethanolamide (PEA) This nicely rounds out the package.

The result is a comprehensive blend of micronutrients and other ingredients designed to support the body’s nutritional needs—month after month.

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf
5.0 out of 5 stars


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also truly worth highlighting is that the products are based on the latest scientific findings and take into account our own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg
5.0 out of 5 stars


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO's highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance
5.0 out of 5 stars


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports the health of my patients.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter
5.0 out of 5 stars


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from alternative practitioners for alternative practitioners, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, alternative practitioner
Potsdam
5.0 out of 5 stars


“I’ve been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results.”

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, naturopath
Trier
5.0 out of 5 stars


“As a naturopath, I specifically apply the TISSO approach to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send
5.0 out of 5 stars


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic therapy approaches and fully meet my high standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby
5.0 out of 5 stars


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel
5.0 out of 5 stars


“I absolutely love working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I really appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

The Cycle Balance Package is a combination of Pro PMS Balance, Pro Biom Anti-Stress and Pro PEA 800. It combines proven plant extracts, PEA, vitamins, minerals, and bacterial cultures. Vitamin B6 helps regulate hormone activity. With the value pack, you save money compared to buying the items separately.

The Cycle Balance Package Contains monk's pepper, ginger, and saffron; three selected bacterial strains—including CEREBIOME® and Lactobacillus rhamnosus GG—as well as palmitoylethanolamide (PEA). This combination is supplemented with vitamin B6, biotin, magnesium, zinc, and copper.

The Cycle Balance Package combines micronutrients with other carefully selected ingredients. Vitamin B6 helps regulate hormonal activity. Biotin, magnesium, and vitamin B6 support the normal functioning of the nervous system and mental health. Magnesium also contributes to normal muscle function and helps reduce tiredness and fatigue. Zinc supports normal fertility and reproduction, as well as protecting cells from oxidative stress.

We recommend the following dosage:

  • Pro PMS Balance
    Take 3 capsules daily with plenty of liquid in the morning with a meal or spread out over several meals
  • Pro Biom Anti-Stress
    Take 1 capsule daily with plenty of liquid during or after a meal
  • Pro PEA 600
    3 capsules daily with plenty of liquid, taken with a meal

The Cycle Balance Package was developed to support hormonal balance during the natural menstrual cycle and is not intended for use during pregnancy. Since there is no longer a typical menstrual cycle during this phase, PMS or menstrual cramps should generally no longer occur. Some ingredients—particularly monk’s pepper and high-dose ginger—are expressly not recommended for pregnant women. There are currently no human studies available on the use of PEA during pregnancy.

We therefore recommend taking the Cycle Balance Package only after consulting a doctor or therapist.

Yes, if you don’t want to swallow the capsules, you can open them and stir the powder into still water, unsweetened herbal tea, or even into foods like granola, yogurt, or applesauce. (Please do not add it to hot beverages or foods, as heat can destroy sensitive active ingredients.) To prevent oxidation or interactions between the ingredients caused by prolonged exposure to air, you should take the capsule contents immediately after opening.
Please note: Pro PMS Balance contains, among other ingredients, ginger and monk’s pepper extracts. Both have a strong, distinctive flavor—ginger, in particular, can taste spicy.

PMS (premenstrual syndrome) refers to physical and emotional symptoms that occur during the second half of the menstrual cycle—usually a few days before the start of a period. Typical PMS symptoms include mood swings, irritability, fatigue, breast tenderness, food cravings, water retention, and sleep problems. The severity can vary from month to month. PMS is not a disease, but rather a normal part of the menstrual cycle that affects many women—to varying degrees.

PMS (premenstrual syndrome) affects many women and can have significant physical and emotional effects—such as mood swings, fatigue, irritability, or pain before a period.

PMDD (Premenstrual Dysphoric Disorder) is a less common but significantly more severe form of cycle-related symptoms. It is characterized by severe mood swings, anxiety, or sensory overload and can significantly interfere with daily life. PMDD is considered a distinct menstrual disorder requiring treatment and should be diagnosed by a doctor.

The menstrual cycle is divided into four phases: menstruation, the follicular phase, ovulation, and the luteal phase. During the luteal phase—that is, the days following ovulation until the next period—hormonal changes occur that are responsible for many PMS symptoms. A woman’s cycle lasts an average of 28 days, but can vary from person to person. Hormonal fluctuations during the cycle affect not only fertility but also emotional balance, performance, and pain sensitivity.

Dysmenorrhea refers to painful menstrual periods—that is, menstrual cramps. It is caused by increased contractions of the uterine muscles, which are often accompanied by cramps, back pain, or nausea. A distinction is made between primary dysmenorrhea (without any identifiable organic cause) and secondary dysmenorrhea (associated with underlying conditions such as endometriosis). The primary form is particularly common among young women.

Just give us a call, Send us an email at info@tisso.de Or send us your question using our contact form. You can reach us here.

CUSTOMER REVIEWS

5
Based on 4 reviews

Andrea Schmitt

Verified Buyer

I recommend this product
I notice how my cycle normalizes with the intake of the capsules.

Laureen Rauch

Verified Buyer

I recommend this product
I have been using these products for several months now and can wholeheartedly recommend them to every woman. I struggle a lot with PMS and these products have really made it easier. I generally love the products from Tisso. The only issue I keep encountering is the customer service. Unfortunately, it is not friendly and also not accommodating. But that doesn't say anything about the great products.

Ina S.

Verified Buyer

I recommend this product
A great combination, I am glad to have tested these products.

Madlen Müller

Verified Buyer

I recommend this product
The products are very well coordinated with each other. The compatibility is very good. I still need to observe the effect more closely.

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND
Hände reichen eine Holzschüssel mit Salat über einen gedeckten Tisch im Freien
Product Category
Minerals
Lachende Frau mit blonden Locken hält die Hand vor den Mund, dazu das Frauensymbol
Scope of Application
Menstrual Cycle and PMS
A woman is tasting a green smoothie in the kitchen
Blog
Diet for PMS and Menstrual Cramps – Relieving Symptoms