Anti-Stress Package Plus—packaging for Pro Omnineuro, Pro Magnesium, Pro Somnia Relax, and Pro Biom Anti-Stress
Pro Magnesium, Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Omnineuro, each containing several capsules; features: gluten-free, fructose-free
Easy to use, daily: Add Pro Magnesium to a liquid. Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Omnineuro—a tip for swallowing, the “nod trick”: 1. Place the capsule on your tongue, 2. Take a sip of water, 3. Tuck your chin toward your chest, 4. Swallow
vegetarian
fructose-free
gluten-free
yeast-free
Tested for harmful substances
of course
additive-free

Dietary supplements

Anti-Stress Package Plus

Premium Combo Pack with Magnesium and Biotin for Nerves & Mental Health: Probiotics , plant extracts, magnesium, and B vitamins. Biotin and magnesium support, for example, nerve health and mental well-being. Get the package deal now!

  • 4-in-1 Bundle: Anti-Stress Basic Combo plus Pro Omnineuro
  • Better value than buying individually—exclusively in this bundle
  • with Lactium®, saffron (Safr’Inside™), and patented asparagus extract (ETAS®50) 
  • Selected bacterial strains: CEREBIOME® and Lactobacillus rhamnosus GG
  • plus taurine, L-carnosine, vitamins B6 and B12, folate, biotin, and triple-strength magnesium 
  • Vitamins B6, B12, and magnesium support, for example, nerve function, mental health, and energy metabolism
vegetarian
fructose-free
gluten-free
yeast-free
Tested for harmful substances
of course
additive-free
159,94 €
Tax included. Shipping calculated at checkout.
Product available – delivered to you in 1–4 daysin-house development
Developed in collaboration with therapists

Over 8,000 doctors and naturopaths
. See what the therapists have to say

PZN:

Premium Formula with Magnesium and Biotin for Nerves & Mental Health: Bacterial cultures, plant extracts, magnesium, and B vitamins. Biotin and magnesium support, for example, the nervous system and mental health. Take advantage of this special package deal now!

Health Claims

  • Biotin contributes to healthy energy metabolism and the normal functioning of the mind and nervous system.
  • Magnesium supports healthy muscle function, normal energy metabolism, healthy mental and nervous system function, and the reduction of tiredness and fatigue.
  • Vitamins B6 and B12 contribute to normal energy metabolism and, like folate, to healthy mental function.
  • Folic acid also helps reduce tiredness and fatigue.

PRODUCTDOSAGERECOMMENDED SERVING SIZE (Please refer to any additional information on the packaging)
PRO BIOM ANTI-STRESS1 capsuleTake with plenty of liquid during or after a meal
PRO SOMNIA RELAX2–4 capsulesTake with plenty of liquid. If you take the capsules right before bedtime, it is recommended that you lie on your right side for 10 minutes to allow for faster release of the active ingredients.
PRO MAGNESIUM4.5 g = 2 slightly heaping measuring spoonsTake with 200 ml of liquid throughout the day, ideally between meals
PRO OMNINEURO1 x 6 capsulesTake with plenty of liquid with a meal


Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.  
Do not exceed the recommended daily intake.

Store in a cool, dry place away from light.

Keep out of the reach of small children.

Please leave the desiccant packet in the can. It contains food-grade silica gel and protects the product from moisture.

Special Notes:

Pro Biom Anti-Stress
Not suitable for pregnant or breastfeeding women or individuals under the age of 18. Do not consume with other dietary supplements containing saffron.

Pro Magnesium
Magnesium doses exceeding 250 mg may have a laxative effect in sensitive individuals.

The container contains measuring spoons and dry pouches that are not intended for consumption.

Pro Omnineuro
Not suitable for pregnant women, nursing mothers, or children under 18 years of age.
Do not take on an empty stomach.
Do not consume this product together with other products that contain green tea.
Do not exceed 800 mg of EGCG per day.

Pro Biom Anti-Stress Ingredientsper daily dose%NRV*
Bacterial cultures5 x 10⁹ CFU¹-
CEREBIOME®: Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-1753 x 10⁹ CFU¹-
Lactobacillus rhamnosus GG2 x 10⁹ CFU¹-
Saffron extract (Safr’Inside™)30 mg-
Biotin7.5 µg15
*Percent of the Daily Reference Intake (DRI), according to the Food Information Regulation (LMIV)
¹colony-forming units (total bacterial count of at least 5 x 10⁹ CFU until the end of the best-before date)
CEREBIOME® is a registered trademark of Danstar Ferment AG.
Safr’Inside™ is a registered trademark of Activ’inside.
Pro Somnia Relax Ingredientsper daily dose (2 CAPS)(4 CAPS)%NRV*(4 CAPS)
Lactium® (milk protein hydrolysate)150 mg(300 mg)--
ETAS®50**100 mg(200 mg)--
of which asparagus extract (Asparagus officinalis)50 mg(100 mg)--
Magnesium (magnesium bisglycinate)75 mg(150 mg)20(40)
*Percent of the Daily Reference Intake, according to the Food Information Regulation (LMIV)
**ETAS® is a registered trademark of Amino Up Co., Ltd. in JAPAN.
Pro Magnesium Ingredientsper daily dose%NRV*
Magnesium375 mg100
from magnesium lactate175 mg-
from magnesium pidolate150 mg-
from magnesium bisglycinate50 mg-
Resistant dextrin2,680 mg-
*Percent of the recommended daily intake, according to LMIV
Pro Omnineuro Ingredientsper daily dose%NRV*
Ashwagandha root extract (KSM-66®)300 mg-
of which withanolides15 mg-
Blueberry extract80 mg-
Broccoli extract300 mg-
Pomegranate extract (Pomanox®)250 mg-
Griffonia extract50 mg-
Decaffeinated green tea extract (Sunphenon®)300 mg-
of which EGCG135 mg-
L-carnosine500 mg-
Taurine650 mg-
Sophora japonica L. extract158 mg-
of which quercetin150 mg-
Rosemary extract150 mg-
Vitamin B6 (pyridoxal-5'-phosphate)15 mg1071
Folate (Quatrefolic® - (6S)-5-methyltetrahydrofolate) Folic acid ((6S)-5-methyltetrahydrofolic acid)400 μg200
Vitamin B12 (methylcobalamin)250 µg10,000
*Percent of the recommended daily intake, according to the Food Information Regulation (LMIV). Pomanox® is a registered trademark of Euromed S.A.
Sunphenon® is a registered trademark of Taiyo Kagaku Co., Ltd.
Quatrefolic® is a registered trademark of Gnosis S.p.A.

Ingredients:

Pro Biom Anti-Stress:
Potato starch; Coating agent: hydroxypropyl methylcellulose; Lactobacillus helveticus Rosell®-52; Bifidobacterium longum Rosell®-175; Lactobacillus rhamnosus GG; Saffron extract (Crocus sativus L.); bulking agent: gum arabic (acacia fiber); antioxidant: L-ascorbic acid; biotin
No flavor enhancers, preservatives, or artificial colors.

Pro Somnia Relax:
Magnesium bisglycinate (52.5%); Coating agent: hydroxypropyl methylcellulose; Lactium® (milk protein hydrolysate) (13.2%); ETAS®50 (Asparagus officinalis extract) (8.8%); rice flour
No flavor enhancers, preservatives, or artificial colors.

Pro Magnesium:
Resistant dextrin; magnesium L-lactate dihydrate (25.0%); magnesium pidolate (24.8%); magnesium bisglycinate chelate
(8.9%); anti-caking agent: silicon dioxide
Contains no flavor enhancers, preservatives, or artificial colors.

Pro Omnineuro:
Taurine (19.9%); Coating agent: hydroxypropyl methylcellulose; L-carnosine (15.3%); broccoli extract; decaffeinated green tea extract (9.2%); pomegranate extract (7.6%); ashwagandha root extract; Sophora japonica L. extract (quercetin); rosemary extract (4.6%); blueberry extract; Griffonia extract (5-HTP); vitamin B12 (methylcobalamin) (0.8%); vitamin B6 (pyridoxal-5'-phosphate) (0.5%); Folic acid ((6S)-5-methyltetrahydrofolic acid, glucosamine salt)
No flavor enhancers, preservatives, or artificial colors.

Your legal guarantee rights
LEGAL GUARANTEE Minimum two-year legal guarantee protection for goods sold in the European Union. Consumers can claim their rights under the legal guarantee of conformity, for example if goods: do not match the description; do not function as intended. Sellers are liable for any lack of conformity which existed when the goods were delivered, and which becomes apparent within the legal guarantee period. Sellers in such a situation are required to offer: free repair or free replacement; in some cases, a price reduction or full reimbursement. Some countries have a longer legal guarantee period. For second-hand goods, a shorter period may apply, but not less than one year. For more information on your rights in a specific country, scan the QR code below or ask the seller. europa.eu/youreurope/guarantees What to do if you receive non-conforming goods: 1 Contact the seller as soon as possible to report the issue; 2 Provide proof of purchase, such as a receipt, invoice, or bank statement. Sellers and producers may also offer commercial guarantees, which apply independently from the legal guarantee. For example, you may see this GARAN label representing a commercial guarantee of durability offered by the producer at no additional cost and covering the entire good.

Open the legal guarantee notice on Your Europe

NATURE AND RESEARCH EFFECTIVELY COMBINED
From practice for people.
NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH
Junge Frau entspannt nach der Arbeit – Symbolbild für Stressabbau, innere Ruhe und Burnout-Prävention
Junge Frau entspannt nach der Arbeit – Symbolbild für Stressabbau, innere Ruhe und Burnout-Prävention

Support for the Nervous System, Mental Health, and Energy Metabolism

Everyday life is full of stressors—whether it’s work, always having to be available, or having little time to relax. This makes it all the more important to ensure a balanced intake of nutrients that support the nervous system and mental well-being.

The Anti-Stress Package Plus combines four products: Pro Biom Anti-Stress, Pro Somnia Relax, Pro Magnesium, and Pro Omnineuro.

It uniquely includes:

  • three selected bacterial strains
  • ten plant extracts, including saffron (Safr’Inside™), green asparagus (ETAS®50), ashwagandha root, blueberries, broccoli, and decaffeinated green tea
  • the milk peptide Alpha-Casozepine (Lactium®)
  • L-Carnosine and Taurine
  • the mineral Magnesium
  • the Vitamins B6, B12, folate, and biotin

Our in-house scientific team has developed such a carefully selected combination.

Vitamins B6, B12, biotin, and magnesium, for example, contribute to the healthy functioning of the nervous system and mental health, as well as energy metabolism. Vitamins B6, B12, folate, and magnesium help reduce tiredness and fatigue.

Entspannt liegende Frau – Symbolbild für ganzheitliche Balance von Darm und Psyche
Entspannt liegende Frau – Symbolbild für ganzheitliche Balance von Darm und Psyche

Selected bacterial cultures, saffron, and biotin

Our gut flora, also known as the microbiome, consists of about 38 trillion bacteria. These account for roughly 98% of all the bacteria in the body and form the first layer of the intestinal barrier. In Pro Biom Anti-Stress contains unique bacterial strains, carefully selected by our scientific team: CEREBIOME® containing the bacterial strains Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175, as well as the bacterial strain Lactobacillus rhamnosus GG combined.

Our Pro Biom Anti-Stress also contains the High-quality microencapsulated saffron extract (Safr’Inside™) as well as Biotin. Biotin, for example, contributes to the healthy functioning of the nervous system and the mind and supports energy metabolism. It is also important for healthy mucous membranes—including those in the intestines.

Paar bei Sonnenuntergang an der Küste – Symbolbild für innere Ruhe, Cortisolregulation und mentale Entlastung
Paar bei Sonnenuntergang an der Küste – Symbolbild für innere Ruhe, Cortisolregulation und mentale Entlastung

Magnesium Meets Innovative Nutrients

Many people are familiar with the feeling of having trouble winding down in the evening. A balanced intake of nutrients that support the healthy functioning of the nervous system and the mind can play an important role here. For example, in Pro Somnia Relax and Pro Magnesium the valuable mineral Magnesium equal to in three forms Contains: as bisglycinate, L-lactate, and highly active oxide.

Magnesium contributes to Reduction of tiredness and fatigue and supports the Function of the Mind and the Nervous System. In addition, it is beneficial for healthy energy metabolism.

In Pro Somnia Relax, magnesium has been carefully combined with milk peptides by our scientific team Alpha-Casozepine (Lactium®) and the patented Green asparagus extract (ETAS®50). Pro Omnineuro also contains a proven blend of eight additional plant extracts (ashwagandha root, blueberries, pomegranate, broccoli, decaffeinated green tea, Griffonia, rosemary, and Sophora japonica L.) and in addition Taurine, L-carnosine, vitamins B6 and B12, and folate.

ALSO AVAILABLE IN THIS VERSION FROM US

Anti-Stress Package—Packaging for Pro Magnesium, Pro Somnia Relax, and Pro Biom Anti-Stress
Pro Magnesium, Pro Somnia Relax, and Pro Biom Anti-Stress, each containing several capsules; features: gluten-free, fructose-free
Anti-Stress Package
5 (3)
Probiotic bacteria, plant extracts, biotin, and magnesium to support normal nervous system and mental function. Includes a volume discount.
92,96 € Includes sales tax; shipping not included

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also truly worth highlighting is that the products are based on the latest scientific findings and take into account our own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO's highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports the health of my patients.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from alternative practitioners for alternative practitioners, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, alternative practitioner
Potsdam


“I’ve been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results.”

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, naturopath
Trier


“As a naturopath, I specifically apply the TISSO approach to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic therapy approaches and fully meet my high standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel


“I absolutely love working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I really appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

The Anti-Stress Package Plus is a 4-in-1 combination of Pro Biom Anti-Stress, Pro Somnia Relax, Pro Magnesium and Pro Omnineuro. It combines selected bacterial cultures, plant extracts, magnesium, selected B vitamins, taurine, and L-carnosine. Vitamins B6, B12, biotin, and magnesium contribute to the normal functioning of the nervous system and energy metabolism, as well as to normal mental function.

The package combines selected micronutrients, plant extracts, and bacterial cultures:

  • Psychobiotics (CEREBIOME®) with Lactobacillus helveticus & Bifidobacterium longum
  • the probiotic lactic acid bacterium Lactobacillus rhamnosus GG
  • Plant extracts, including those from saffron (Safr’Inside™) and green asparagus (ETAS®50), ashwagandha root, broccoli, blueberries, pomegranate, and green tea (EGCG)
  • the milk peptide alpha-casozepine (from Lactium®)
  • Magnesium in three forms: oxide, lactate, and bisglycinate
  • Biotin (vitamin B7) and the bioactive B vitamins B6, B12, and folate
  • Neuroprotective taurine and L-carnosine

The Anti-Stress Package Plus combines selected micronutrients, plant extracts, and bacterial cultures. Vitamins B6, B12, biotin, and magnesium contribute to the normal functioning of the nervous system and energy metabolism, as well as to normal psychological function. Vitamins B6, B12, folate, and magnesium also help reduce tiredness and fatigue.

We recommend the following dosage:

  • Pro Biom Anti-Stress
    Take 1 capsule daily with plenty of liquid, on an empty stomach or at least 30 minutes before a meal
  • Pro Somnia Relax
    Take 2 capsules daily with plenty of water, 30–60 minutes before bedtime
  • Pro Magnesium
    4.5 g daily (2 slightly heaping measuring spoons), dissolved in 200 ml of liquid and taken throughout the day, ideally between meals
  • Pro Omnineuro
    6 capsules daily with plenty of liquid, taken with a meal

The TISSO Anti-Stress Package Plus is not suitable for pregnant women, breastfeeding women, or people under the age of 18. The saffron extract in Pro Biom Anti-Stress and the green tea extract (EGCG) in Pro Omnineuro are considered potentially risky in high doses during pregnancy. Although our products each contain a moderate and safe dosage, we recommend taking the Anti-Stress Package Plus during pregnancy and while breastfeeding only after consulting a doctor or therapist.

Yes, at Pro Biom Anti-Stress, Pro Somnia Relax and Pro Omnineuro You can open the capsules if you don't want to swallow them. You can mix the contents into still water, unsweetened herbal tea, or even foods such as granola, yogurt, or applesauce. Please avoid hot beverages or foods, as heat can destroy sensitive ingredients. You should take the capsule contents immediately after opening to prevent oxidation and interactions between the ingredients.

Pro Magnesium It comes in powder form and can be stirred directly into liquids or food. As with other products, be sure to consume it promptly after mixing and do not use hot liquids. It has a pleasant taste thanks to natural watermelon flavoring and stevia.

Stress is the body’s natural response to specific demands or pressures. It activates the nervous system, releases stress hormones such as adrenaline and cortisol, and puts the body on high alert. In the short term, stress can boost performance. However, if the stress persists, chronic stress can impair health—for example, through sleep disturbances, exhaustion, digestive problems, or an increased susceptibility to infections.

Burnout describes a state of physical, emotional, and mental exhaustion that is usually caused by prolonged stress, being overwhelmed, and a lack of time to recharge. Typical symptoms include a loss of energy, lack of motivation, sleep disturbances, irritability, and the feeling that one can no longer cope with daily life. Taking early steps to manage stress and support mental and emotional well-being can help prevent burnout or promote recovery.

Resilience refers to a person’s psychological resilience—that is, the ability to cope with crises, stress, and challenges, and even to grow from them. Resilient people are able to regain their stability more quickly after difficult situations. Resilience can be strengthened, for example, through targeted stress management strategies, self-care, social support, and a balanced intake of essential nutrients for the nervous system and mental health.

Cortisol is a hormone produced in the adrenal glands that plays a central role in stress. In the short term, it helps mobilize energy reserves and prepare the body for stressful situations. However, if cortisol levels remain elevated over an extended period, this can have negative effects on sleep, the immune system, metabolism, and mental health. Balanced regulation of the cortisol response is therefore important for long-term health and well-being.

The Anti-Stress Package Plus also includes the product Pro Omnineuro. This complements the Anti-Stress Package including other selected ingredients such as L-carnosine, taurine, quercetin, additional B vitamins, and plant extracts—including those from ashwagandha root, broccoli, blueberries, and green tea, among others.

Just give us a call, Send us an email at info@tisso.de Or send us your question using our contact form. You can reach us here.

CUSTOMER REVIEWS

4.8 Based on 4413 reviews

Rating

Carmen Ubrig

Verified Buyer

Super products.

Super products.

Walter Krößer

Verified Buyer

Prompt delivery and great product

Prompt delivery and great product. I will order again.

Werner Treichl

Verified Buyer

Product

Product, quality

Daniela Burkard

Verified Buyer

Delivery Good and Fast

Delivery good and fast, good and high-quality products

Martina

Verified Buyer

I am very satisfied with the vitamin…

I am very satisfied with the vitamin D3. The quality is excellent and taking it is easy and straightforward. I feel completely comfortable with it and am glad I chose this product. The price-performance ratio is also right. I can definitely recommend it and would buy it again at any time!

caros

Verified Buyer

The products from Tissot are very…

The products from Tissot are very high quality and help me find a healthy balance

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND
Grafik „Funktionen der 8 essenziellen B-Vitamine“: Nervensystem und Energiestoffwechsel – B1, B2, B3, B5, B6, B7 und B12; Bildung roter Blutkörperchen – B2, B6 und B12; Immunsystem und Homocystein-Stoffwechsel – B6, B9 (Folat) und B12; Zellteilung – B9 und B12
Product Category
Vitamins
Frau mit geschlossenen Augen atmet tief ein
Scope of Application
Stress
A woman is sleeping with her head resting on her arms at a desk
Blog
Burnout – When Exhaustion Becomes an Overwhelming Burden