Dietary supplements

Anti-Stress Package

Premium Combo Pack with Magnesium and Biotin for Nerves & Mental Health: Selected bacterial cultures and high-quality plant extracts. Plus biotin and magnesium for the nervous system, mental health, and energy. Get this great deal on the combo pack now!

  • 3-in-1 Bundle with Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Magnesium
  • Better value than buying individually—exclusively in this bundle
  • with Lactium®, saffron (Safr’Inside™), and patented asparagus extract (ETAS®50)
  • Selected bacterial strains: CEREBIOME® and Lactobacillus rhamnosus GG
  • Biotin and magnesium for the nervous system, mental well-being, and energy metabolism
  • Also available as the Anti-Stress Package Plus: with Pro Omnineuro
vegetarian
fructose-free
gluten-free
yeast-free
Tested for harmful substances
of course
additive-free
Price: 92,96 €
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Product available—delivered to you in 1–4 daysin-house development
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PZN:

Premium Formula with Magnesium and Biotin for Nerves & Mental Health: Selected bacterial cultures and high-quality plant extracts. Plus biotin and magnesium for the nervous system, mental well-being, and energy. Take advantage of this special package deal now!

Health Claims

  • Biotin contributes to healthy energy metabolism and the normal functioning of the mind and nervous system.
  • Magnesium helps reduce tiredness and fatigue, supports healthy muscle function, promotes normal energy metabolism, and supports the healthy functioning of the mind and nervous system.

PRODUCTDOSAGERECOMMENDED SERVING SIZE (Please refer to any additional information on the packaging)
PRO BIOM ANTI-STRESS1 capsuleTake with plenty of liquid during or after a meal
PRO SOMNIA RELAX2–4 capsulesTake with plenty of liquid. If you take the capsules right before bedtime, it is recommended that you lie on your right side for 10 minutes to allow for faster release of the active ingredients.
PRO MAGNESIUM4.5 g = 2 slightly heaping measuring spoonsTake with 200 ml of liquid throughout the day, ideally between meals


Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.  
Do not exceed the recommended daily intake.

Store in a cool, dry place away from light.

Keep out of the reach of small children.

Please leave the desiccant packet in the can. It contains food-grade silica gel and protects the product from moisture.

Special Notes:

Pro Biom Anti-Stress
Not suitable for pregnant or breastfeeding women or individuals under the age of 18. Do not consume with other dietary supplements containing saffron.

Pro Magnesium
Magnesium doses exceeding 250 mg may have a laxative effect in sensitive individuals.

The container contains measuring spoons and dry pouches that are not intended for consumption.

Pro Biom Anti-Stress Ingredientsper daily dose%NRV*
Bacterial cultures5 x 10⁹ CFU¹-
CEREBIOME®: Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-1753 x 10⁹ CFU¹-
Lactobacillus rhamnosus GG2 x 10⁹ CFU¹-
Saffron extract (Safr’Inside™)30 mg-
Biotin7.5 µg15
*Percent of the daily recommended intake, according to the Food Information Regulation (LMIV)
¹colony-forming units (total bacterial count of at least 5 x 10⁹ CFU until the end of the best-by date)
CEREBIOME® is a registered trademark of Danstar Ferment AG.
Safr’Inside™ is a registered trademark of Activ’inside.
Pro Somnia Relax Ingredientsper daily dose (2 caps)(4 caps)%NRV*(4 caps)
Lactium® (milk protein hydrolysate)150 mg(300 mg)--
ETAS®50**100 mg(200 mg)--
of which asparagus extract (Asparagus officinalis)50 mg(100 mg)--
Magnesium (magnesium bisglycinate)75 mg(150 mg)20(40)
*Percent of the Daily Reference Intake, according to the Food Information Regulation (LMIV)
**ETAS® is a registered trademark of Amino Up Co., Ltd. in JAPAN.
Pro Magnesium Ingredientsper daily dose%NRV*
Magnesium375 mg100
from magnesium lactate175 mg-
from magnesium pidolate150 mg-
from magnesium bisglycinate50 mg-
Resistant dextrin2,680 mg-
*Percent of the recommended daily intake, according to LMIV

Ingredients:

Pro Biom Anti-Stress:
Potato starch; Coating agent: hydroxypropyl methylcellulose; Lactobacillus helveticus Rosell®-52; Bifidobacterium longum Rosell®-175; Lactobacillus rhamnosus GG; Saffron extract (Crocus sativus L.); bulking agent: gum arabic (acacia fiber); antioxidant: L-ascorbic acid; biotin
No flavor enhancers, preservatives, or artificial colors.

Pro Somnia Relax:
Magnesium bisglycinate (52.5%); Coating agent: hydroxypropyl methylcellulose; Lactium® (milk protein hydrolysate) (13.2%); ETAS®50 (Asparagus officinalis extract) (8.8%); rice flour
Contains no flavor enhancers, preservatives, or artificial colors.

Pro Magnesium:
Resistant dextrin; magnesium L-lactate dihydrate (25.0%); magnesium pidolate (24.8%); magnesium bisglycinate chelate
(8.9%); anti-caking agent: silicon dioxide
Contains no flavor enhancers, preservatives, or artificial colors.

NATURE AND RESEARCH EFFECTIVELY COMBINED
From practice for people.
NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH
Junge Frau entspannt nach der Arbeit – Symbolbild für Stressabbau, innere Ruhe und Burnout-Prävention
Junge Frau entspannt nach der Arbeit – Symbolbild für Stressabbau, innere Ruhe und Burnout-Prävention

Support for the Nervous System, Mental Health, and Energy Metabolism

Everyday life is full of stressors—whether it’s work, the need to be constantly available, or a lack of time to relax. This makes it all the more important to ensure a balanced intake of nutrients that support the nervous system and mental well-being.

The Anti-Stress Package combines three products: Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Magnesium. It uniquely includes:

  • three selected bacterial strains
  • Plant extracts made from high-quality Saffron (Safr’Inside™) and green asparagus (ETAS®50)
  • the milk peptide Alpha-Casozepine (Lactium®)
  • micronutrients Magnesium and biotin.

Our in-house scientific team has developed such a carefully selected combination.

Biotin, for example, contributes to the healthy functioning of the nervous system and the mind, as well as to energy metabolism. And magnesium helps, among other things, reduce tiredness and fatigue and supports the normal functioning of the nervous system and the mind.

Entspannt liegende Frau  – Symbolbild für ganzheitliche Balance von Darm und Psyche
Entspannt liegende Frau  – Symbolbild für ganzheitliche Balance von Darm und Psyche

Selected bacterial cultures, saffron, and biotin

Our gut flora, also known as the microbiome, consists of about 38 trillion bacteria. These account for roughly 98% of all the bacteria in the body and form the first layer of the intestinal barrier. In Pro Biom Anti-Stress contains unique strains of bacteria, carefully selected by our scientific team: CEREBIOME® containing the bacterial strains Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175, as well as the bacterial strain Lactobacillus rhamnosus GG combined.

Our Pro Biom Anti-Stress also contains the High-quality microencapsulated saffron extract (Safr’Inside™) as well as Biotin. Biotin, for example, contributes to the healthy functioning of the nervous system and the mind and supports energy metabolism. It is also important for healthy mucous membranes—including those in the intestines.

Paar bei Sonnenuntergang an der Küste – Symbolbild für innere Ruhe, Cortisolregulation und mentale Entlastung
Paar bei Sonnenuntergang an der Küste – Symbolbild für innere Ruhe, Cortisolregulation und mentale Entlastung

Magnesium Meets Innovative Nutrients

Many people are familiar with the feeling of not being able to wind down right away in the evening. A balanced intake of nutrients that support healthy nervous system and mental function can play an important role here. For example, Pro Somnia Relax and Pro Magnesium contain the valuable mineral Magnesium equal in three forms Contains: as bisglycinate, L-lactate, and pidolate.

Magnesium contributes to Reduction of tiredness and fatigue and supports the Function of the Mind and the Nervous System. In addition, it is beneficial for healthy energy metabolism.

In Pro Somnia Relax, magnesium has been carefully combined with milk peptides by our scientific team Alpha-Casozepine (Lactium®) and the patented Extract fromgreen asparagus (ETAS®50).

ALSO AVAILABLE IN THIS VERSION FROM US

Anti-Stress Package Plus—packaging for Pro Omnineuro, Pro Magnesium, Pro Somnia Relax, and Pro Biom Anti-Stress
Pro Magnesium, Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Omnineuro, each containing several capsules; features: gluten-free, fructose-free
Anti-Stress Package Plus
5 (1)
Anti-Stress Package Plus: Bacterial cultures, plant extracts, B vitamins, and magnesium. Includes, among other ingredients, biotin and magnesium to support the nervous system and mental well-being.
Price: 159,94 € Includes sales tax; shipping not included

TESTIMONIALS FROM TISSO PARTNERS

Portrait photo of Iwonna Riesenfeld, a naturopath from Düsseldorf
Iwonna Riesenfeld, naturopath
Düsseldorf
5.0 out of 5 stars


“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also truly worth highlighting is that the products are based on the latest scientific findings and take into account our own studies and observational data.”

Portrait photo of Joachim Fehrenbacher, a physical therapist from Schramberg
Joachim Fehrenbacher, Physical Therapist
Schramberg
5.0 out of 5 stars


"Since we take a holistic approach to caring for people, we really enjoy working with TISSO's highly effective products. A trusting partnership of this kind is possible with only a few companies."

Portrait photo of Ailyn Moser, a naturopath from Radolfzell on Lake Constance
Ailyn Moser, naturopath
Radolfzell on Lake Constance
5.0 out of 5 stars


“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports the health of my patients.”

Portrait photo of Nicole Bode, a naturopath from Höxter
Nicole Bode, alternative medicine practitioner
Höxter
5.0 out of 5 stars


“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from alternative practitioners for alternative practitioners, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it!”

Portrait photo of Andreas Klose, a naturopath from Potsdam
Andreas Klose, alternative practitioner
Potsdam
5.0 out of 5 stars


“I’ve been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results.”

Portrait photo of Sandra Oettel, a naturopath from Trier
Sandra Oettel, naturopath
Trier
5.0 out of 5 stars


“As a naturopath, I specifically apply the TISSO approach to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Portrait photo of Ulrike Goldberg, a naturopath from Senden
Ulrike Goldberg, alternative medicine practitioner
Send
5.0 out of 5 stars


“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic therapy approaches and fully meet my high standards.”

Portrait photo of Antje Hein, a naturopath from Haby
Antje Hein, alternative medicine practitioner
Haby
5.0 out of 5 stars


“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Portrait photo of Diana Klein, a naturopath from Sprockhövel
Diana Klein, alternative medicine practitioner
Sprockhövel
5.0 out of 5 stars


“I absolutely love working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I really appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO.”

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

The Anti-Stress Package from TISSO is a holistically balanced combination of products designed to provide support during stressful times. It contains a top-notch combination of three high-quality supplements—Pro Biom Anti-Stress, Pro Somnia Relax, and Pro Magnesium—that are specifically designed to help reduce inner restlessness, regulate the stress response, and promote mental balance.

The package combines selected micronutrients, plant extracts, and bacterial cultures:

  • Psychobiotics (CEREBIOME®) with Lactobacillus helveticus & Bifidobacterium longum
  • the probiotic lactic acid bacterium Lactobacillus rhamnosus GG
  • Plant extracts from saffron (Safr’Inside™) and green asparagus (ETAS®50)
  • the milk peptide alpha-casozepine (from Lactium®)
  • Magnesium in three forms: pidolate, lactate, and bisglycinate
  • Biotin (Vitamin B7)

The ingredients in this product help the body on multiple levels to reduce stress levels and cope better with stress. Psychobiotics promote balance in the gut, which is closely linked to mental health. Herbal extracts from saffron and green asparagus, as well as alpha-casozepine, help promote calm and regulate the cortisol response. Magnesium and biotin support the nervous system, mental well-being, and energy metabolism—for greater resilience and inner stability.

We recommend the following dosage:

  • Pro Biom Anti-Stress
    Take 1 capsule daily with plenty of liquid, on an empty stomach or at least 30 minutes before a meal
  • Pro Somnia Relax
    Take 2 capsules daily with plenty of liquid 30–60 minutes before bedtime
  • Pro Magnesium
    Take 2 x 3.5 g daily (equivalent to 1 level measuring spoon each time) in 200 ml of liquid.

The TISSO Anti-Stress Package is not suitable for pregnant women, nursing mothers, or individuals under the age of 18. The saffron contained in Pro Biom Anti-Stress is considered, in high doses, to potentially induce labor and has not been sufficiently studied for these life stages. Even though our product contains a moderate and safe dosage, we recommend taking the Anti-Stress Package during pregnancy and while breastfeeding only after consulting a doctor or therapist.

Yes, at Pro Biom Anti-Stress and Pro Somnia Relax You can open the capsules if you don’t want to swallow them. You can mix the contents into still water, unsweetened herbal tea, or even into foods like granola, yogurt, or applesauce. Please avoid hot drinks or foods, as heat can destroy sensitive ingredients. You should take the capsule contents immediately after opening to prevent oxidation and interactions between the ingredients.

Pro Magnesium It comes in powder form and can be stirred directly into liquids or foods, as it is tasteless. The same rule applies here: consume it promptly after mixing and do not use hot liquids.

Stress is the body’s natural response to specific demands or pressures. It activates the nervous system, releases stress hormones such as adrenaline and cortisol, and puts the body on high alert. In the short term, stress can boost performance. However, if the stress persists, chronic stress can impair health—for example, through sleep disturbances, exhaustion, digestive problems, or an increased susceptibility to infections.

The term “burnout” is commonly used to describe states of severe exhaustion. Medical evaluation and treatment should be provided by appropriately qualified professionals.

Resilience refers to a person’s psychological resilience—that is, the ability to cope with crises, stress, and challenges, and even to grow from them. Resilient people are able to regain their stability more quickly after difficult situations. Resilience can be strengthened, for example, through targeted stress management strategies, self-care, social support, and a balanced intake of essential nutrients for the nervous system and mental health.

Cortisol is a hormone produced naturally by the body in the adrenal cortex. It belongs to the group of glucocorticoids.

Yes, the Anti-Stress Package is also available in a Plus version. The Anti-Stress Package Plus also includes the product Pro Omnineuro—with L-carnosine, taurine, eight selected plant extracts, and bioactive B vitamins. It is particularly suitable for people who want to support their stress management in an even more targeted way or build it up over the long term.

→ Anti-Stress Package Plus

Just give us a call, Send us an email at info@tisso.de Or send us your question using our contact form. You can reach us here.

CUSTOMER REVIEWS

4.8
Based on 4348 reviews

Laura Drexler

Verified Buyer

I recommend this product
Really good!
Really good!

Isabella Wedenig

Verified Reviewer

I recommend this product
Working with nature...free from laboratories and manipulations...may the goal remain quality.
The ingredients, herbal composition, selection, very harmonious, genuine, you can still taste the herb itself. Helps immediately, noticeably. Serious and clear processing when ordering, processed with a consciousness for nature right into the hands of the customer. Pro Intest..

Margrit

Verified Reviewer

I recommend this product
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Order processing, shipping, and product Pro Mucosa all 100 % 👍👍☺️

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I recommend this product
Everything is great
Everything is great, quality, price, performance

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Verified Buyer

I recommend this product
Maximum precision thanks to Italy
Maximum precision thanks to Italy

Aneta Wozny

Verified Buyer

I recommend this product
Super Product
Super product! Fast delivery

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND
Grafik „Funktionen der 8 essenziellen B-Vitamine“: Nervensystem und Energiestoffwechsel – B1, B2, B3, B5, B6, B7 und B12; Bildung roter Blutkörperchen – B2, B6 und B12; Immunsystem und Homocystein-Stoffwechsel – B6, B9 (Folat) und B12; Zellteilung – B9 und B12
Product Category
Vitamins
Frau mit geschlossenen Augen atmet tief ein
Scope of Application
Stress
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Blog
Burnout – When Exhaustion Becomes an Overwhelming Burden