Pro Flex

Pro Flex combines native, fully bioactive Type II collagen (UC-II®) with frankincense extract, calcium fructoborate (FruiteX-B®), and joint nutrients derived from eggshell membrane (EggNovo OVOMET®). This provides targeted and long-lasting relief from joint inflammation and pain.

Pro Flex is ideal for anyone who wants to provide targeted support for their joints—especially when facing increased strain in daily life, during sports, or as they age.

The combination of selected ingredients in Pro Flex is designed to support normal joint function. Through the synergy of type II collagen, frankincense extract, calcium fructoborate, and nutrients from eggshell membrane, the formula provides a beneficial supplement for flexible and resilient joints.

Yes. If you don't want to swallow the capsules, you can open them and stir the powder into still water, unsweetened herbal teas, or even foods such as granola, yogurt, or applesauce. (Please do not add it to hot drinks or foods!) Consume immediately after opening.

Oral tolerance is a mechanism through which your body learns not to have an allergic reaction to every antigen in food. The immune system in the gut is constantly confronted with unknown and potentially dangerous substances from food. To avoid falling into a constant state of attack, it must recognize harmless antigens as such and tolerate them—hence the term “oral tolerance.”

Regulatory T cells play a key role in this process. These specialized immune cells are responsible for suppressing unwanted immune responses. They are produced in a manner specific to the antigen in the lymphatic tissue of the intestine and travel via the lymphatic vessels to other organs in the body, where they prevent attacks against “their” antigen. UC-II® collagen harnesses this mechanism to build immune tolerance to the free collagen in the joint through the oral intake of native collagen.

Native collagen is natural collagen with an unaltered protein structure, just as it occurs in the body. When proteins such as collagen have their spatial structure destroyed—for example, by heat—they are referred to as denatured. Native collagen is therefore also referred to as undenatured or non-denatured collagen. Denatured proteins generally lose their biological function. The intact, native molecular structure of UC-II® collagen is crucial for building tolerance to the body’s own joint collagen.

UC-II® is an extract derived from raw chicken sternal cartilage, obtained through a patented process at low temperatures and without enzymatic hydrolysis. Unlike conventional collagen hydrolysate, UC-II® contains native, insoluble type II collagen with an unaltered protein structure. The content is standardized to at least 3 percent undenatured type II collagen. This is sufficient to achieve the desired effect of oral tolerance with a low daily dose.

Native collagen is collagen in its natural form. Due to its molecular size, it is virtually indigestible by the body. It reaches the lymphatic tissue in the small intestine intact and can establish oral tolerance to the body’s own collagen there.

Hydrolyzed collagen, or collagen hydrolysate, is denatured collagen. To produce it, the natural collagen molecule is heated and then broken down into smaller peptides and amino acids with the help of enzymes. These are more easily absorbed and provide the body with the necessary building blocks to produce its own collagen. Hydrolyzed and native collagen thus support joint health in two completely different ways.

That’s difficult. Unless, for example, you like meat with cartilage or fish bones—preferably raw, so that the native collagen isn’t destroyed by the heat of cooking or frying. Native type II collagen is found almost exclusively in human and animal cartilage tissue. Your body produces this collagen from the protein building blocks you consume in your diet. These do not have the complete collagen structure necessary for the development of oral tolerance.

FruiteX-B® is currently the world’s only patented raw material for nature-identical calcium fructoborate. Calcium fructoborate is a highly bioavailable, organic boron complex that is also found naturally in plants. FruiteX-B® has been extensively studied and has been classified as a safe food by the European Food Safety Authority (EFSA) since 2021.

Pro Flex can generally be taken without any problems even by people with fructose intolerance. The calcium fructoborate (FruiteX-B®) it contains has a very low fructose content of 0.18 grams per daily dose. In cases of fructose intolerance, small amounts of up to 25 grams per day are usually still well tolerated. Only in the rare case of hereditary fructose intolerance (HFI) is the threshold one gram or less.

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