vegan

fructose-free

lactose-free

gluten-free

yeast-free

hypoallergenic

Tested for harmful substances

of course

additive-free

Dietary supplements

Pro Ferra Ferment

For gently replenishing iron stores without side effects: Pro Ferra Ferment provides fermented iron derived from the koji fungus Aspergillus oryzae, combining the good tolerability of plant-based iron with the high bioavailability of a divalent iron salt. Completely free of the usual digestive discomfort. It also supports iron metabolism with vitamin C and selected B vitamins.

21 mg of highly bioavailable iron per capsule—ideal for iron deficiency
particularly gentle and well-tolerated thanks to slow-release iron
Buffered vitamin C to support iron absorption from food
Includes vitamins B2, B6, B12, and folate (folic acid) for more energy and vitality

vegan

fructose-free

lactose-free

gluten-free

yeast-free

hypoallergenic

Tested for harmful substances

of course

additive-free

35,95 €

Choose your volume discount:

Volume discounts cannot be combined with subscription plans.

35,95 €

Content: 33 g | 1 kg = 1.089,39 €
Tax included and shipping calculated at checkout

~~35,95 €~~ 34,15 €

PZN:18220529

To gently replenish iron stores : Pro Ferra Ferment provides fermented iron sulfate derived from the koji fungus Aspergillus oryzae, combining the good tolerability of plant-based iron with the high bioavailability of a divalent iron salt. It also supports iron metabolism with vitamin C and selected B vitamins.

Health Claims:

Iron contributes to energy metabolism, the formation of red blood cells and hemoglobin, oxygen transport in the body, immune system function, the reduction of fatigue, and cognitive function.
Vitamin C increases iron absorption.
Vitamins C, B2, B6, and B12 contribute to energy metabolism.
Vitamin B2 contributes to iron metabolism.
Vitamins B6 and B12 help produce red blood cells.
Folic acid contributes to normal blood formation and helps reduce fatigue.

It is recommended to take 1 capsule daily with plenty of liquid, on an empty stomach or at least 1 hour before or after a meal.
Do not exceed the recommended daily intake.

Notes:
Dietary supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.
Store in a cool, dry place away from light.
Keep out of the reach of small children.
Please leave the desiccant packet in the can. It contains food-grade silica gel and protects the product from moisture.

Ingredients	per daily dose	%NRV*
Iron (from Aspergillus oryzae culture (inactivated) enriched with iron sulfate)	21 mg	150
Vitamin C (sodium L-ascorbate)	100 mg	125
Vitamin B2 (riboflavin)	1.4 mg	100
Vitamin B6 (pyridoxal-5'-phosphate)	1.4 mg	100
Folic acid/folate (5-methyltetrahydrofolic acid)	100 µg	50
Vitamin B12 (methylcobalamin)	2.5 µg	100
*Percent of the recommended daily intake, according to the Food Information Regulation (LMIV)

Ingredients:

Aspergillus oryzae culture (inactivated) enriched with iron sulfate (42.2%); Vitamin C (sodium L-ascorbate) (20.5%); pullulan; filler: microcrystalline cellulose; vitamin B6 (pyridoxal-5'-phosphate) (0.4%); Vitamin B2 (riboflavin) (0.3%); Vitamin B12 (methylcobalamin on mannitol); Folic acid ((6S)-5-methyltetrahydrofolic acid, glucosamine salt)

No flavor enhancers, preservatives, or artificial colors.

Pollutant analyses conducted by independent laboratories

Quality and safety are TISSO's top priorities. That's why we have our products tested regularly by independent laboratories.

The contaminant analyses we conduct ensure that our products consistently meet the highest quality standards. To Pro Ferra Ferment The test results from a DAkkS-accredited laboratory are available for you to download.

Your legal guarantee rights

LEGAL GUARANTEE Minimum two-year legal guarantee protection for goods sold in the European Union. Consumers can claim their rights under the legal guarantee of conformity, for example if goods: do not match the description; do not function as intended. Sellers are liable for any lack of conformity which existed when the goods were delivered, and which becomes apparent within the legal guarantee period. Sellers in such a situation are required to offer: free repair or free replacement; in some cases, a price reduction or full reimbursement. Some countries have a longer legal guarantee period. For second-hand goods, a shorter period may apply, but not less than one year. For more information on your rights in a specific country, scan the QR code below or ask the seller. europa.eu/youreurope/guarantees What to do if you receive non-conforming goods: 1 Contact the seller as soon as possible to report the issue; 2 Provide proof of purchase, such as a receipt, invoice, or bank statement. Sellers and producers may also offer commercial guarantees, which apply independently from the legal guarantee. For example, you may see this GARAN label representing a commercial guarantee of durability offered by the producer at no additional cost and covering the entire good.

Open the legal guarantee notice on Your Europe

NATURE AND RESEARCH EFFECTIVELY COMBINED

From practice for people.

NATURAL DIETARY SUPPLEMENTS FOR YOUR HEALTH

Aufgeschlagenes Notizbuch mit der Zeichnung von Pilzen, daneben Gräser

Fermented iron from the koji fungus

Iron is essential for blood formation, oxygen transport, and the supply of energy to cells. A deficiency therefore primarily causes paleness, fatigue, and weakness. Women are usually the ones affected, but

including vegetarians and vegans. In women, this is due to menstruation and pregnancy; in those on a meat-free diet, it is due to the low bioavailability of plant-based iron.

Anyone who has ever needed to take supplemental iron knows this: Common supplements containing iron sulfate and other divalent iron salts (Fe²⁺) often upset the stomach and intestines. They release the trace element quickly into the body—which makes them very efficient, on the one hand, but irritates the mucous membranes in the digestive tract, on the other. Although plant-based iron is better tolerated, it is hardly absorbed at all, since it is predominantly present in the trivalent form (Fe³⁺) and is tightly bound.

Highly bioavailable and well-tolerated iron

A noble mold makes it possible: Our iron comes from a unique, patented fermentation process using the koji mold Aspergillus oryzae. In this process, a starter culture made from rice and the koji fungus is enriched with ferrous sulfate, which the fungus incorporates into its cells during the subsequent fermentation. The iron embedded in this way has been shown to be released in the body much more slowly—and thus more gently—than the isolated iron sulfate often prescribed for iron deficiency.¹ Nevertheless, it enters the bloodstream in an equally high concentration, thus offering a naturally derived alternative to plant-based iron sources that are also well-tolerated but have very low bioavailability.

No Chance for Free Radicals

The rapid release and absorption of conventional iron can exceed the binding capacity of the iron-transport protein transferrin, especially at high doses. The result is excess free iron in the blood, which promotes the formation of oxygen radicals. The steady and slow absorption of our fermented iron effectively prevents such excessive iron uptake.

Premium Formula: Fermentation Meets Vitamin Complex

The fermentation of rice with Aspergillus fungi (koji fermentation) has a centuries-old tradition in Asia, particularly in Japan, and serves as the basis for the preparation of soy sauce, miso, and sake, among other products. Aspergillus oryzae has been granted GRAS status (GRAS = generally considered safe) by the U.S. Food and Drug Administration (FDA) and is therefore classified as safe.

Vitamin C helps the body absorb more iron from food. It converts trivalent iron into readily available bivalent iron, thereby increasing the amount of iron absorbed from plant-based foods. Pro Ferra Ferment contains stomach-friendly, buffered vitamin C in the form of sodium L-ascorbate.

Vitamins B2, B6, B12, and folic acid, together with iron, provide energy and support blood formation. In Pro Ferra Ferment, vitamins B6, B12, and folic acid are already present in their active coenzyme form, which the body can utilize directly.

Iron Fact Sheet

Iron in the Body

Iron is essential for blood formation, oxygen transport, and the supply of energy to cells. It also plays an important role in the immune system and in cognitive function. The human body contains about 3 to 5 grams of iron, roughly 80% of which is active, functional iron: in the hemoglobin of red blood cells, in the myoglobin of muscle cells, and in iron-containing enzymes, including those in the mitochondrial respiratory chain. The remaining 20% is stored as ferritin and hemosiderin in the liver and spleen or circulates in the blood bound to transferrin.

Heme iron vs. non-heme iron

The body obtains iron exclusively from food, in the form of heme iron and non-heme iron. The divalent iron (Fe²⁺) bound in the heme molecule—from which the term derives—is found exclusively in animal-based foods, particularly in meat, sausage, and liver.

Plants primarily provide non-heme iron. This is iron in an ionized, mostly trivalent form (Fe³⁺). However, trivalent iron must first be converted to divalent iron before it can be absorbed in the intestine and therefore has significantly lower bioavailability. Certain plant compounds, such as phytates, oxalates, and tannins, further inhibit iron absorption.

Deficiency or Increased Need

Iron deficiency is one of the most common nutritional deficiencies worldwide. It most often affects women, but vegetarians and vegans are also at risk. In women, it is caused by menstruation and pregnancy; in those who follow a meat-free diet, it is due to the low bioavailability of plant-based iron.

Since too much iron can be harmful, high-dose supplements should only be taken if a deficiency has been diagnosed. An increased need for iron, on the other hand, can be easily met with a much lower-dose dietary supplement such as our Pro Ferra Ferment.

Sources

1 Bries, A. E., Wang, C., Agbemafle, I., Wels, B., & Reddy, M. B. Assessment of Acute Serum Iron, Non-Transferrin-Bound Iron, and Gastrointestinal Symptoms Following 3 Weeks of Consumption of Iron-Enriched Aspergillus oryzae Compared with Ferrous Sulfate. Curr. Dev. Nutr. 3, (2019)

2 Reddy, M. B., Armah, S. M., Stewart, J. W., & O’Brien, K. O. Iron Absorption from Iron-Enriched Aspergillus oryzae Is Similar to That of Ferrous Sulfate in Healthy Female Subjects. Curr. Dev. Nutr. 2, (2018)

TESTIMONIALS FROM TISSO PARTNERS

Iwonna Riesenfeld, naturopath

Düsseldorf

“I’ve been working as a naturopath for 15 years, and I’ve been recommending TISSO products for just as long. What continues to impress me time and again is the outstanding quality and the well-thought-out formulation of each product. What’s also truly worth highlighting is that the products are based on the latest scientific findings and take into account our own studies and observational data.”

Joachim Fehrenbacher, Physical Therapist

Schramberg

"Since we take a holistic approach to caring for people, we really enjoy working with TISSO's highly effective products. A trusting partnership of this kind is possible with only a few companies."

Ailyn Moser, naturopath

Radolfzell on Lake Constance

“As a naturopath, I greatly value my collaboration with TISSO, as their work focuses on both our microbiome and our mitochondria. Their holistic dietary supplements combine active ingredients from orthomolecular medicine, phytotherapy, and mycotherapy. For me, TISSO is a reliable partner that supports the health of my patients.”

Nicole Bode, alternative medicine practitioner

Höxter

“Products that aren’t just good for my patients, but that I also trust. At TISSO, they take the time to provide detailed advice, which is why I could never do without this partnership! A wide variety of products from alternative practitioners for alternative practitioners, where you can be sure that people’s well-being comes first—not money. I’m happy to stay here and can only recommend it!”

Andreas Klose, alternative practitioner

Potsdam

“I’ve been a naturopath for twenty years and have been working with TISSO products for over seven years. What pleases me most is receiving positive feedback from patients and seeing the results reflected in their test results.”

Sandra Oettel, naturopath

Trier

“As a naturopath, I specifically apply the TISSO approach to particularly challenging situations that children and adolescents face. Together, we successfully address the root causes of gastrointestinal problems, allergies, asthma, and food intolerances in my patients, which leads to improved health and well-being.”

Ulrike Goldberg, alternative medicine practitioner

Send

“To me, TISSO stands for excellent quality ingredients and transparent production of formulations based on the latest scientific findings. TISSO products are an integral part of my holistic therapy approaches and fully meet my high standards.”

Antje Hein, alternative medicine practitioner

Haby

“I’ve been using TISSO products for my patients and myself for several years now. I am very happy to have found a company like TISSO that prioritizes proven quality and effectiveness. I have very high standards when it comes to dietary supplements, and thanks to TISSO, I can provide my patients with sound advice and care in this area.”

Diana Klein, alternative medicine practitioner

Sprockhövel

“I absolutely love working with TISSO. The products are of very high quality, and I’ve had many positive and rewarding experiences with them—both with my patients and for myself. In addition to the products, I really appreciate the team behind the company. They’re always helpful, knowledgeable, and friendly. I highly recommend TISSO."

TISSO.
From practice for people.

That's what makes us special

IN-HOUSE DEVELOPMENT BASED ON SCIENTIFIC RESEARCH

Our experts review countless studies for each formula.

HIGHLY BIOAVAILABLE AND OPTIMALLY COMBINED

We always select our raw materials so that they are as effective as possible.

BRAND-NAME QUALITY FROM OUR OWN PRODUCTION

We manufacture our products ourselves so that we can always guarantee the highest quality.

NUTRITIONAL APPROACH PROVES SUCCESSFUL IN PRACTICE

More than 8,000 doctors and alternative practitioners are already successfully using our holistic MitoBiom® approach.

EXPERTISE SINCE 1999

Take advantage of our extensive experience with high-quality dietary supplements.

GUARANTEE OF THE HIGHEST PURITY

We continuously inspect our products in accordance with the highest quality standards.

FREQUENTLY ASKED QUESTIONS

Who is Pro Ferra Ferment suitable for?

Pro Ferra Ferment It is suitable for anyone who wants to gently and effectively replenish their iron stores—especially women of childbearing age, pregnant women, breastfeeding women, as well as vegetarians and vegans. People with increased iron needs or a diagnosed deficiency can also benefit from this gentle and well-tolerated form of iron.

What sets Pro Ferra Ferment apart from conventional iron supplements?

Many conventional iron supplements release iron very quickly. This can cause irritation in the gastrointestinal tract. Pro Ferra Ferment In contrast, iron that has been fermented using the koji fungus is released much more slowly, is particularly gentle on the stomach, and is highly bioavailable—without causing the typical digestive discomfort.

Can Pro Ferra Ferment cause stomach problems?

Pro Ferra Ferment It is particularly well tolerated because the iron is released slowly and evenly through fermentation with the koji fungus. This is gentle on the gastrointestinal tract—without the typical side effects that many people associate with conventional iron supplements.

Can I combine Pro Ferra Ferment with other dietary supplements?

Yes, Pro Ferra Ferment can be easily combined with other dietary supplements. It is particularly beneficial to combine it with Vitamin C, since it helps the body absorb iron—this is already in Pro Ferra Ferment included. Other vitamins and minerals can also be taken as supplements.

How long should I take Pro Ferra Ferment as an iron supplement?

The duration of use depends on individual needs. If iron deficiency has been diagnosed, the supplement should be taken until iron stores are replenished. This can take several weeks to months. During specific life stages, such as pregnancy or breastfeeding, as well as in cases where long-term support is needed, it is recommended to discuss the duration of use individually with a therapist.

Which vitamins enhance the iron-absorption effects of Pro Ferra Ferment?

Vitamin C increases iron absorption from plant-based foods, thereby enhancing the effect. The B vitamins B2, B6, B12, and folate are important partners in iron metabolism: They promote blood formation, contribute to energy metabolism, and help reduce fatigue. These very vitamins are found in Pro Ferra Ferment already included—in an easily absorbable and active form.

CUSTOMER REVIEWS

4.9

Based on 48 reviews

Britta G.

Verified Buyer

I recommend this product

Well tolerated. My friend's ferritin level has increased because of this.

Anzahl

Verified Buyer

I recommend this product

So far, I cannot judge it yet But I trust in its effect 💕🕊️💞

Doris Müller

Verified Buyer

I recommend this product

The product is very well tolerated

Andrea

Verified Buyer

I recommend this product

Good compatibility

Frau Brigitte Orenz

Verified Buyer

I recommend this product

I have often prescribed it. I haven't taken it myself yet, but I would prefer it over other products. It is well tolerated and has not caused any stomach issues, as I have been informed.

David Geer

Verified Buyer

I recommend this product

"cured" the depression of my girlfriend

FACT-BASED KNOWLEDGE FOR YOUR HEALTH

READ, LISTEN, UNDERSTAND

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Product Category

Minerals

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Scope of Application

Vegetarian and Vegan Diets

Podcast

#11 Iron – Deficiency, Requirements, and Sources