MITOBIOM® CONCEPT
The Gut—A Key Pillar of the MitoBiom® Concept
Cardiovascular diseases, chronic inflammatory bowel diseases, type 2 diabetes, neurodegenerative diseases, autoimmune diseases, and nearly all other classic lifestyle-related diseases have their origins in an unhealthy gut—or in mitochondrial dysfunction. This is demonstrated by modern research and many years of clinical practice. Both the microbiome and the mitochondria are equally sensitive to stress, with consequences for the entire body.
Here, you’ll gain an initial overview of how dysbiosis and the resulting leaky gut develop, what a thorough analysis and measures to restore a healthy intestinal barrier entail, and what role mitochondria play in this process. Both approaches—treating the gut, including the microbiome and mitochondria—are combined in the MitoBiom® concept. This can help improve the health of people with chronic illnesses in particular. You can learn more in the seminars on the MitoBiom® concept offered by the TISSO Academy.
How does a diseased intestine develop?
The intestinal wall consists of four protective layers that together form what is known as the intestinal barrier. They prevent undigested food particles, harmful substances, and pathogenic bacteria from entering the bloodstream.
These protective layers include:
- the gut microbiome
- the mucus layer rich in immunoglobulins
- the intestinal mucosa
- the gut-associated immune system, which accounts for about 80% of all the body's immune cells
However, the following factors can lead to dysbiosis and damage to the mucosal barrier (leaky gut):
- unhealthy diet
- Food Additives
- Food Intolerances
- chronic stress
- Taking certain medications, such as antibiotics
- Environmental toxins (e.g., pesticides, heavy metals)
- Cesarean section
Leaky gut allows bacterial antigens such as lipopolysaccharides (LPS), dietary components, or environmental toxins to pass unimpeded through the intestinal wall. This leads to the activation of the immune system and, as a result, to systemic chronic inflammatory reactions. These often smolder asymptomatically for a long time until they eventually manifest as chronic diseases.
What are the signs of an unhealthy gut?
A diseased intestine can manifest itself in a variety of ways throughout the entire body. The following disorders or diseases, which are mentioned in the adjacent image, frequently occur:
Gut Check — With Comprehensive Analysis
For your patients, you can easily have the condition of their intestines analyzed in a lab using a stool sample.
The most significant parameters in this context are, above all:
- Flora Status / Microbiome Analysis
- Alpha-1-antitrypsin
- Calprotectin
- Zonulin
- Digestive residues
- Bile acid
- Pancreatic elastase
- secretory IgA (sIgA)
In addition, it is advisable to test for 25(OH)-vitamin D3 in the blood.
You can learn more about the sophisticated analytics and the precise relationships in the seminars on the MitoBiom® concept offered by the TISSO Academy.
Restoring a Healthy Gut
Based on the analysis, individual goals and measures are identified to restore or maintain a healthy intestinal barrier, including the microbiome.
The specific goals include, above all:
- Building and Maintaining a Healthy Gut Flora
- anti-inflammatory measures
- Mucosal Regeneration
- Promotes Digestion
- Improving Mucosal Immunity
Mitochondrial Treatment: The Second Key Pillar of the MitoBiom® Concept
Adequate energy production in the epithelial cells—and thus healthy mitochondria—are essential for proper functioning of the intestinal epithelium. However, mitochondrial dysfunction not only leads to an energy deficiency but is also associated with increased production of reactive oxygen species, which in turn have a direct damaging effect on the intestinal microbiome and can also cause inflammation in the intestinal epithelium.
On the other hand, a leaky gut leads to systemic, silent inflammation associated with oxidative and nitrosative stress, which can easily damage the mitochondria in particular. The result is a decrease in mitochondrial ATP production and, consequently, in cellular function, which can ultimately lead to chronic diseases.
In a holistic approach to treating chronic diseases, strengthening the mitochondria is therefore the second key pillar, alongside treating the gut, including the microbiome. The MitoBiom® approach is based precisely on this combined strategy.
MitoBiom® Concept — Continuing Education Courses
Would you like to learn more about the MitoBiom® concept and start applying it right away? In the seminars offered by the TISSO Academy, experienced and knowledgeable instructors will provide you with the theoretical and practical knowledge you need to implement the MitoBiom® concept safely and confidently. After just one seminar, you’ll be able to start applying it right away—even in combination with other methods.
You’ll learn how to apply this concept in practice and master the associated analytical methods through hands-on, module-based seminars that we offer regularly at various locations. In addition, specialized seminars and free webinars provide you with a wide range of professional insights and perspectives on the MitoBiom® concept. In our media library, you’ll find recordings of all our webinars as well as videos about our products.
The TISSO Academy service team ensures a pleasant atmosphere and optimal support before, during, and after our training courses (seminare@tisso.de). Our customer service team, our seminar service, and the experts on our technical hotline are happy to provide you with advice and assistance.
